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Liver & Gallbladder

24.9--Liver and GallBladder

Liver Largest Internal Organ, and Heaviest Gland in Body; inferior to diaphragm and occupies most of right hypochondriac and epigastric regions
GallBladder Pear-shaped sac, located on inferior surface of liver
Right Lobe and Left Lobe Larger/Small respectively. Divided by falciform ligament
Falciform Ligament A mesentaric fold of the peritoneum, spanning from diaphram, anterior abdominal wall, and visceral peritoneum
Right Lobe Parts Inferior quadrate lobe, and posterior caudate lobe
Ligamentum Teres Round Ligament--extends from liver to umbilicus; remnant of umbilical cord
Coronary Ligaments Suspend liver from diaphragm
Gall--Fundus Projects downward beyond inferior border of liver
Gall--Body and Neck Project superiorly
Hepatocytes One cell thick; line up in hepatic laminae (rows); membrane forms grooves for canaliculi for bile secretion
Hepatic Laminae Rows of heptocytes, spaces in between cells allow for bile secretion
Bile Yellow, brownish or olive green liquid secreted; emulsify lipids into suspensions, and assist in absorption of lipids into lacteals
Bile Canaliculi Small Ducts in between hepatocytes that collect bile and pass into ductules and bile ducts.
Bile Ducts Left and Right hepatic ducts; exit liver as common hepatic duct; joins with cystic duct of gall bladder to form common bile duct
Hepatic Sinusoids Highly permeable blood capillaries b/w hepati laminae receive oxygenated blood from hepatic artery and nutrient rich deoxygenated blood from portal vine. Converge into Central Vein
Portal Triad Bile Duct, Hepatic Artery, and Hepatic Portal Vein
Hepatic Lobule Hexagon shape; three corners of portal triad
Portal Lobule Exocrine Function; bile secretion
Hepatic Acinus Oval mass that includes portions of two hepatic lobules. Short axis is branches of portal triad. Zone 1 = glucose, zone 3 = fat accumulate, Zone 2= structural
Kuppffer Cells Destroy worn out white and red blood cells. Phagocytic
Sphincter of Oddi Bile goes back into cystic duct for storage between meals; closes off duodenum.
Liver Function Carb metabolism (glucose level, conversion), lipid metabolism, protein metabolism (deamination), drug processing, excretion of bilirubin, Synth of bile, Storage (vit and glycogen), Phagocytosis, Vit D activation
Bilirubin Derived fom heme of red blood cells (aged). Secreted into bile. Mostly metabolized by small intestine and bacteria; eliminated in feces.
Created by: 100000434525601