Busy. Please wait.
Log in using Clever

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

M6 13-005

Exam 14: Drugs & The Immune System

T lymphocytes form specialized cells in lymphoid tissue and organs to provide cellular immunity
B lymphocytes form antibodies to provide humoral immunity
Antibodies gamma globulins are specific for particular antigens
Active Immunity body produces specific antibodies to combat infection caused by specific antigens or microbes (Vaccines)
Artificially Acquired Active Immunity occurs when an individual is given a killed or weakened antigen, which stimulates the formation of antibodies against the antigen.
Cell-Mediated Immunity (CMI) result of the activity of many leukocyte actions, reactions, and interactions that range from simple to complex.
T lymphocytes and macrophages ork together in CMI to destroy the antigen.
T lymphocytes defend against viral, fungal and some bacterial infections
Humoral Immunity antibody-antigen response.
Antigen a substance, usually a protein, which stimulates the body to produce antibodies.
Antibody globulin (protein) produced by the B lymphocytes as a defense against an antigen.
Naturally Acquired Active Immunity occurs when the person is exposed to a disease, experiences the disease, and the body manufactures antibodies to provide future immunity to the disease.
Passive Immunity provided to the person by ready-made antibodies from another human or from an animal source. Immediate immunity to the invading antigen, but only last a short time. Your body did not have to do it.
Immunoglobulins bind with antigens and promote the destruction of invading cells by either hindering antigens by neutralizing their toxins.
Immunoglobulins: Action Immunity from immune globulins is rapid, but short-lived (up to 3 months).
RHo (D) immune globulin (Rhogam) Given postpartum as a suppressant to prevent future hemolytic diseases of newborns Prevent production of anti-RHoD antibodies in RHoD negative pts who were exposed to RHoD positive blood.
Hepatitis B immune globulin (Engerix-B, Recombivax HB) provides passive immunity to hepatitis B.
Rabies immunoglobin rabies prophylaxis
Tetanus immunoglobulin post-exposure tetanus prophylaxis, tetanus treatment.
Active immunization with vaccine or toxoids produces prolonged immunity... How long? years
Immunosuppressants (Compromised) Suppress certain T-lymphocyte cell lines, preventing their involvement in an immune response Induces an immunocompromised state similar to cancer patients and those with AIDS They are all generally given in conjunction with corticosteroids.
cytokine release syndrome (CRS) High fever and chills, headache, dizziness, malaise, tremors of hands, N/V/D, chest pain, tachycardia, muscle and joint pain, SOB
Relative contraindications, depending on the patient’s diagnosis (Immunosupressants) 1) Renal or hepatic failure 2) Hypertension 3) Concurrent radiation therapy.
cytokine release syndrome (CRS): Seen with what meds? basiliximab, daclizumab, and muromomab
Cyclosporine: Fun facts 1) Drugs that alter liver-metabolizing processes may change the effect of cyclosporine. 2) Concurrent digestion of grapefruit or grapefruit juice increases absorption and should be avoided.
Neutrophils (normal value) 3000-7000 mm3.
Neutropenia < 1000 mm3
Severe neutropenia < 500 mm3
Immunosuppressant Implementation Thorough hand washing. Neutropenic precautions. meticulous mouth, skin and perineal care. No standing water.
Antineoplastics (Chemotherapy) to kill every neoplastic cell and produce a cure
cell cycle-nonspecific: cytotoxic (cell killing) in any phase of the cycle
cell cycle-specific aimed at a specific cell cycle phase
Antineoplastics: Assessment Monitor for bone marrow depression. Assess for bleeding. Assess for signs of neutropenia. Monitor for increased fatigue, dyspnea, and orthostatic hypotension. Monitor intake and output ratios, appetite, and nutritional intake.
Created by: jtzuetrong



Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards