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Acute Diarrhea Open
Johnson case opening acute diarrhea
| Question | Answer |
|---|---|
| Definition of Diarrhea | - >200-250 gm/day of stool - Decrease in fecal consistency - Abnormal frequency and liquidity of stool with greater than 3 loose/watery stools in 24 hours |
| Acute diarrhea duration | <14 days |
| Chronic diarrhea duration | >30 days |
| Persistent diarrhea duration | >14 days but <30 days |
| Paradoxical diarrhea | Stool oozing around an impaction |
| Dysentery | -Frequent watery stools, often with blood/pus/mucus -Clinically characterized by pain, tenesmus, dehydration -Bacillary: Shigella ssp -Amebic: Entamoeba histolytica |
| Enteritis | Inflammation of small intestine |
| Gastritis | Inflammation of stomach |
| Gastroenteritis | Inflammation of both stomach and intestine |
| Colitis | Inflammation of colon |
| Enterocolitis | Inflammation of both large and small intestine |
| Tenesumus | Painful spasm of urogenital diaphragm accompanied by an urgent desire to evacuate the bowel or bladder and involuntary straining that results in the passage of little to no matter |
| Osmotic Diarrhea | -d/t increased osmotic load -watery -often volume of stool produced <1 L/d -Stops during fast or removal of offending substance |
| Secretory Diarrhea | -Watery -Occurs when secretion of electrolytes and water into the lumen exceeds absorption -Often produces stool volume >1 L/d -Usually doesn't resolve with 2-3 day fast |
| Inflammatory Diarrhea | -Exudative -Mucosal lining inflamed, damage to the mucosal lining or brush border -Structural damage to the mucosa impairs absorption and stimulates secretion -Stool positive for WBCs |
| Malabsorption/Maldigestion | Fatty diarrhea |
| Motility-related Diarrhea | Functional diarrhea, irritable bowel syndrome |
| Organisms causing viral infection | -Rotavirus -Norovirus -Adenovirus |
| Organisms causing bacterial infections | -Salmonella -E. coli -Shigella -Bacillus cereus -Clostridium perfringes -Staphylococcus aureus -Vibrio cholera -Vibrio parahaemolyticus -Yersinia enterocolitica -Campylobacter jejuni -Clostridium difficile -Listeria monocytogenes |
| Organsims causing parasitic infections | -Giardia lamblia -Entamoeba histolytica -Cryptosporidium -Cyclosporoa cayetanensis -Microsporidia -Isospora -Balantidium |
| N/V predominant acute diarrhea | -Bacillus cereus -Staphylococcus aureus |
| Diarrhea predominant small bowel acute diarrhea | Viruses, bacteria, parasites |
| Diarrhea predominant large bowel acute diarrhea | bacteria, parasites |
| Inflammatory bloody acute diarrhea | -Crohn's ileitis -Crohn's colitis -Villous adenoma |
| Inflammatory non-blood acute diarrhea | -Ulcerative colitis -Crohn's colitis -Radiation colitis |
| Drugs/toxins acute diarrhea | -Laxative abuse -Antibiotics -Heavy metals -many more |
| Dietary acute diarrhea | -Food allergy/hypersensitivity -Osmotic causes (lactase deficiency, sugars, sugar alcohols) |
| What situations warrant stool culture collection? | -Immunocompromised patients -Co-morbidites -Severe, inflammatory diarrhea (including bloody diarrhea) -Patients with underlying inflammatory bowel disease in whom the distinction between a flare and superimposed infection is critical -Food handlers |
| Medically significant diarrhea | -Profuse watery diarrhea w/ hypovolemia -Passage of many small volume stools w/ blood and mucus -Blood -Temp >101.3 F -Pass >6 unformed stools/24 h -Severe ab pain -Hospitalized/elderly/antibiotics/immunocompromised -Pregnant |
| Basic treatment of acute diarrhea | -Rehydration: oral, IV -Antibiotics -Symptomatic: antidiarrheals, antinausea meds |
| Contraindication for antidiarrheals | Never use antidiarrheals in patients with bloody diarrhea! |