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M6 13-005

Exam 5: Respiratory Meds

2 Types of histamines H1 Receptors & H2 Receptors
H1 Receptors Mediate smooth muscles (Contaction & Dilation)
H2 Receptors Mediate acceleration of heart rate & Gastric secretion
Diphenhydramine, Azatadine, Dimenhydramine, Promethazine, Brompheneramine. Traditional Antihistamines
Fexofenadine (allegra), Loratadine (Claratin) Non-sedating Antihistamines
Common side effects of Antihistamines Drowsiness, sedation, headache, thickening of bronchial secretions, dry mouth, urinary retention
Block histamines antihistamines
Reduces swelling of nasal passages Decongestants
Afrin, Sudafed, Neo-synphrine Adrenergics (Decongestants)
Beconase, Flonase, Nasacort Topical Corticosteroids (Decongestants)
Atrovent Anticholinergic (Decongestant)
Bronchodilators Relax bronchial smooth muscle to dilate bronchi & bronchioles
3 Classes of Bronchodilators Beta-Antagonists, Anticholinergics, Xanthine Derivatives
Beta-Antagonists RELIEF of bronchospasm
Anticholinergics PREVENT bronchoconstriction
Xanthine Derivatives DILATE the airways
First Line Anti-tubercular Pharmacological Profile Inhibits mycobacterial cell wall synthesis & interferes with metabolism
Second line Anti-tubercular Pharmacological Profile Reserved for more Complicated cases. Yup... Thats it.
INH, Ethambutol, Rifmapin, Pyrazinamide First Line Anti-tubercular Pharmacological Profile
Cough Suppressant Anti-tussive
@ Main categories of Anti-tussives Opioids & Non-Opioids
Codine, Hydrocodone Opioids
Dextrorphan, guaifenesin (Robitussin) Non-opioid
Manage episodes of REVERSIBLE bronchoconstriction Antiasthmatics
Adrenergic, Anticholinergic, Bronchodilators, Corticosteroids, Leukotrine Receptor Antagonist, Mast Cell Stabilizers Antiasthmatics
Mediate airway edema, smooth muscle constriction, altered cellular activity Leukotrine Antagonists
Accolate, Singulair Leukotrine Antagonists
Part of the inflammatory pathway that cause bronchoconstriction Leukotrines
Tx of reversible airway obstruction d/t asthma or COPD. Relaxes airway smooth muscle. Bronchodilators
Long acting management of COPD Zanthines
Truphylline, Unipril Zanthines
Increase diaphragmatic contractility Zanthines
Relaxes smooth airway muscle to dilate bronchioles (long term control) Adrenergics
Albuterol, Epinephrine, Salmeterol, Terbutaline Adrenergics
Created by: jtzuetrong