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Nervous system medic
| Question | Answer |
|---|---|
| Atropine is a competitive antagonist of | muscarinic receptors |
| what is an anticholinergic | blocks acetylcholine in the central and peripheral nervous system |
| muscarinic receptors belong to which NS? | parasympathetic nervous system |
| Atropine decreases the tone of which NS and allows which one to predominate? | decreases parasympathetic and allows sympathetic to predominate |
| Mechanism of Epinephrine | Binds and activates adrenergic receptors of the sympathetic nervous system |
| Epinephrine Side effects | jitteriness/anxiety, increased heart oxygen requirement, vessel constriction |
| When is Epinephrine used? | cardiac arrest, severe asthma, local anesthetics |
| What is epinephrine | hormone and neurotransmitter |
| What nervous system uses mostly norepinephrine and epinephrine as neurotransmitters | sympathetic |
| Alpha1 adrenergic receptor (3) | vein constriction, decreased GI activity, uterus contraction |
| Alpha2 adrenergic receptor | inhibits CNS sympathetic outflow |
| Beta1 adrenergic receptor | increases heart rate, heart contraction |
| Beta2 adrenergic receptor | dilates bronchioles, release glucose from liver |
| When is the parasympathetic NS dominant? | at rest |
| When is Atropine used? (3) | slow heart rate, eye drops, dry secretion in mouth or lungs |
| What happens after an overdose of atropine? | Anticholinergic toxidrome |
| Name some anticholinergic side effects | blind, mat, hot, red, dry skin, incontinence, rapid heart rate |
| Mechanism of nikotin | agonist of nicotinic receptors |
| What is acetylcholine | neurotransmitter |
| where is acetylcholine used (3) | pre-ganglionic nerves, post-ganglionic nerves, nerve muscle juntions |