click below
click below
Normal Size Small Size show me how
Fungal RTI- Blue
Fungal infections of the respiratory tract- Blue 1/17/2013
Question | Answer |
---|---|
Dimorphism | Exists in mycelial form in the soil and in yeast form in the body |
Fugal infections are acquired by | Spores from the mycelial form |
Why does the yeast form have a longer life span in the body? | It survives phagocytosis and therefor requires a specific cell-mediated response to be cleared |
Histoplasmosis is common where? | Ohio-Mississippi Valley |
Histoplasmosis growth is commonly associated with guano of | Birds, particularly starlings,chickens and bats |
Histoplasmosis is acquired from | Inhalation of conidia which is converted to yeast in the lungs |
Disease progression of histoplasmosis is associated with | Heavy infecting doses or immunodeficiency |
Constant reinfection and resolution of histolplasmosis is often asymptomatic but presents with | Granulomas in the lungs (common in the midwest) |
Symptoms of progressed histoplasmosis | Flu-like, patchy pneumonia that is chronic and relapsing |
Classic pattern seen in histoplasmosis | Snowstorm or buckshot |
In immunocompromised patients with histoplasmosis, dissemination may occur to | Spleen, Liver, Adrenals |
Coccidiomycosis is commonly seen in regions of | Southwestern US (Desert) |
Peak infection rates of coccidiomycosis are found after a | Desert rain |
Coccidomycosis have a thick wall to protect from | Heat in the Desert |
Coccidomycosis replicates by | Nuclear division which eventually walls off, leading to sacs of endospores |
LIfe cycle of coccidomycosis | Arthrospores are inhaled from desert soil and are converted to yeast. Yeast goes through nuclear division to form spherules which contain endospores which infect |
Coccidomycosis symptoms | Mild, flue-like illness, fever, cough, headache. Resolves in 2-6 weeks |
Treatment for coccidomycosis | Azole drugs, Amphotericin B |
Treatment for histoplasmosis | Azole drugs, Amphotericin B |
North American Blastomycosis differs from Histoplasmosis in that it can also infect | Dogs |
Balstomycosis patients may initially present with | Cutaneous lesions |
Paracoccidiomycosis is limited to which areas | Central and South America, Tropical and Subtropical areas |
Paracoccidiomycosis presents with | Cutaneous or mucocutaneous ulcers, especially in the oral and nasal cavities |