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Tumors

3

QuestionAnswer
Neurofibroma A benign nerve sheath tumor in the peripheral nervous system. Usually found in individuals with NF1.
Glioma A type of tumor that starts in the brain or spine and arises from glial cells. The most common site is the brain. (50.3%)
Meningioma A diverse set of tumors arising from the meninges, the membranous layers surrounding the CNS. Most common primary brain tumor, representing one-third of all such tumors. Usually benign. (20.9%)
Pituitary Adenomas Non-cancerous tumors that occur in the this gland. These are generally divided into three categories dependent upon their biological functioning: benign adenoma, invasive adenoma or carcinomas. (15%)
Nerve Sheath Tumor (Neoplasm) A type of tumor of the nervous system which is made up primarily of the myelin surrounding nerves.
Schwannoma (Neurilemmoma, Neurinoma, Neurolemmoma, Schwann Cell Tumor) Benign nerve sheath tumor of only Schwann cells, (insulates myelin sheath of PNS). Tumor always stay on outside of nerve, but may push possibly causing damage. Slow growing, mostly benign. May come from NF2. 1% form cancer known as neurofibrosarcoma.
Ependymoma (Ependymal) Arises from the ependyma, a tissue of the CNS. Usually, in pediatric cases the location is intracranial, while in adults it is spinal. The common location of these intracranial is the fourth ventricle. Sometimes Choroid Plexus. Can be seen with NF2.
Neuroma A growth or tumor of nerve tissue.
Acoustic Neuroma (Schwannoma, Vestibular Schwannoma, or Neurilemmoma) Arises from cells that form a protective sheath around nerve fibers. Typically grows around the eighth cranial nerve, but can be found around other cranial or spinal nerves.
Chordoma Rare, low grade. Occurs at sacrum, (lower tip of spine), or at base of skull. Originates from residual fetal cells. Invades bone & soft tissue but rarely the brain tissue but can block ventricles, causing hydrocephalus. Can metastasize (spread) or recur.
Craniopharyngioma A type of brain tumor derived from pituitary gland embryonic tissue, that occurs most commonly in children but also in men and women in their 50s and 60s.
Blastoma (suffix) Used to imply a tumor of primitive, incompletely differentiated (or precursor) cells, i.e nephro..., medullo... and retino....
Metastatic Brain Tumors (Brain Metastases) Secondary, or one that begins in another part of the body. Some of the cancer cells may be carried to the brain by the blood or lymphatic fluid, or may spread from adjacent tissue. These are the most common brain tumors and usually seen in middle-age.
Oligodendroglioma A type of mixed glioma that originate from this type of glial cell. Primarily in adults (9.4% of all primary brain and CNS tumors) but are also found in children (4% of all primary brain tumors). The average age at diagnosis is 35 years.
Carcinoma Tumor tissue derived from putative epithelial cells whose genome has become altered or damaged to such an extent that the cells become transformed and begin to exhibit abnormal malignant properties.
Neoplasm An abnormal mass of tissue as a result of the abnormal proliferation (the growth or production of cells by multiplication of parts) of neoplasia.
Adenoma A benign tumor (-oma) of glandular origin. These can grow from many organs including the colon, adrenal glands, pituitary gland, thyroid, prostate, etc. Although these growths are benign, over time may progress malignant. Usually removed with surgery.
Adenocarcinoma An Adenoma that becomes cancerous / malignant.
Primitive Neuroectodermal Tumor (PNET) A neural crest tumor. It is a rare tumor, usually occurring in children and young adults under 25 years of age. After successful chemotherapy or/and radiotherapy the 5 year survival rate is only 7.6-8%.
Glioblastoma Multiforme (GBM) The most common and most aggressive malignant primary brain tumor in humans, involving glial cells and accounting for 52% of all functional tissue brain tumor cases and 20% of all intracranial tumors.
Astrocytomas A type of neoplasm of the brain. Originate in star-shaped brain cells called astrocytes. Does not usually spread outside the CNS and does not usually affect other organs. This is the most common glioma and can occur in most parts of the CNS.
Lipoma Fatty Tumor. Most common benign tumor in adults, often found in neck, shoulders, back, arms. Slow growing, usually round, soft & movable. May run in families. Some result from injury. Tx painful or growing quickly through liposuction or surgery.
Neoplasm Tumor; any new and abnormal growth, specifically one in which cell multiplication is uncontrolled and progressive. These may be benign or malignant.
Types of Astrocytomas (Gliomas): Anaplastic Astrocytoma, GBM, Low-Grade Astrocytoma, Pilocytic Astrocytoma.
Types of Gliomas (Meninges / Neural Crest): NF1, Neurofibroma, Meningioma, Optic Nerve, Astrocytoma, Oligodendroglioma, Mixed Glioma, Carcinoma, Ependymoma, PNET, GBM, Brainstem.
Types of Neoplasm (Nerve Sheath Tumor): Schwannoma, Astrocytomas, Acoustic Neuroma.
Types of Adenomas: Pituitary, Craniopharyngioma, Adenocarcinoma, Polyps.
Types of Schwannoma (Neuromas): NF2, PNS.
Fibromas (Fibroids) Tumors of fibrous or connective tissue that can grow in any organ but commonly grow in the uterus. Although not cancerous, can lead to heavy vaginal bleeding, bladder problems, or pelvic pain or pressure.
Hemangiomas A buildup of blood vessel cells in the skin or internal organs. A common type of birthmark, often occurring in the head, neck, or trunk. They may appear red or bluish in color. Most go away on their own. Tx if interfere with vision, hearing, or eating.
Peripheral Nerve Sheath Tumor (PNST) A nerve sheath tumor in the peripheral nervous system. (8%)
Created by: kmburg5840
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