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Conduction-Brown
Conduction: Microanatomy and Physiology
| Question | Answer |
|---|---|
| The functional layers of the heart | Endocardium (inner lining of heart), Epicardium (Outer lining of the heart), Myocardium (heart muscle) |
| Endocardium | In contact with blood, simple squamous (endothelium), Valves and Ct are outgrowths of endocardium |
| Epicardium | Contains blood vessels, simple squamous (mesothelium), also the same thing as visceral pericardium |
| Myocardium | Cardiac muscle |
| Intercalated Discs allow for | Coordinated heart contractions, connect cytoplasm of each cell to the cytoplasm of neighbors |
| Cardiac nuclei are located | centrally |
| SA node is located in the | Right atria |
| AV node is located in | Septal wall of the right atrium |
| Purkinje cells appear as | slightly transparent, large diameter cardiac myocytes in the endocardium |
| Mesothelial lining | A serious layer that releases fluid to keep the heart from adhering to parietal pericardium |
| Annulus fibrosis | A fibrous skeleton of connective tissue that insulates ventricles from the atria. Only depolarization from the AV node penetrates |
| ___initiate the contraction of the heart | Action potentials |
| Three areas of the heart that have automaticity (spontaneous depolarization) | SA node, AV node, (some)Purkinje fibers |
| "Phase 4" is also known as the | Slow diastolic depolarization |
| Outflow of potassium (Ik) is involved in | Repolarization |
| "Funny channel" (If) is a | inward sodium current when SA node cells have gone down to -60mV (resting minimum potential) |
| "Phase 4" is due to which ion current | If or funny channel which is an influx of sodium |
| Calcium channels opening cause | An influx of calcium which cause a rapid depolarization |
| Norepinephrine binding to Beta1 on the SA node causes | Increase the function of If (funny channel) which increases rate of diastolic depolarization (Sympathetics) |
| M receptors binding with Acetylcholine in the SA node causes | Increase in the potassium channel which decreases rate of diastolic depolarization (Parasympathetics) |
| Conduction rate in SA node | .05 m/s |
| Conduction rate in atria | 1 m/s |
| Conduction rate in AV node | .01-.05 m/s |
| AV nodal conduction is dependent on on voltage-gated _____ channels | Ltype-Calcium |
| Speed of conduction in Purkinje fibers | 4-5 m/s |
Created by:
mcasto
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