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antiinflammatory
pharm test 2
Question | Answer |
---|---|
most effective antiasthmatic drug available | glucocoricoids |
what suppress the inflammation by decreasin synthesis and release of inflammatory mediators, decreases inflitration and activity of inflam cells, decreases edema of the airway mucosa | glucocorticoids |
what is used for phrophylaxis of chronic asthma its a fixed schedule, not PRN | glucocorticoids |
what is the first line therapy of glucocorticoids | inhaled, its safe |
what is the most common side effect of inhaled glucorticoids | oropharyngeal candidasis and dysphonia |
with L-T highe doeses of glucocorticoids you may hae | some adrenal suppression |
maximum improvement of glucocorticoids | may take up to 4 weeks |
what's prolonged therapy can cause adrenal suppression, osteoporosis hyperglycemia pud growth suppression in children | glucocorticoids |
initially very large doses of glucocorticoids can be given for how long to bring a sever attack under control when IV aminophylline and sympathomimetics have proven inadequate | as long as 5 days |
avoid giving steroids when | on an empty stomach |
what also decreases airway mucus production and increases the number of bronchial eta2 receptoras as well as their responsiveness to beta 2 agonist | glucocorticoids |
oral glucocorticoids are given for | thos with severe asthma not controlled with bronchodilator therapy, high risk of toxicity, tx as brief as possible will not cause significant adverse effects |
gargle and spit after each dose of | inhaled flucocorticoids |
how are glucocorticoids administered | inhalation PO or IV |
what do you want to check when given glucorticoids | blood sugar due to hyperglycemia |