AML Word Scramble
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| Question | Answer |
| What are the types of translocation is AML associated with? | t(8;21) - RUNX, inv(16), t(15;17) - APL --> Down Syndrome, t(9,11) |
| What is the median age for onset of AML? | 65 years |
| What is the cytoplasmic granule of AML? | Auer Rods |
| What are the CD Positivity? | CD 13,14 and CD33 positive |
| Which type of translocation is a favourable prognosis? | t(8; 21) - RUNX |
| What are the clinical findings Acute Promyelocytic Leukemia? | 1. Disseminated intravascular coagulation due to the release of thrombotic substance into the granules. 2. Younger age (median age 35-40). 3. t(15;17) translocation - APL-RAR |
| What Tx can be used for Acute Promyelocytic leukemia or T(15:17)? | All-trans retinoic acid (ATRA) can overcome the translocation. |
Created by:
Jameel D. Wilson
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