Therapeuticmeds
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pathophysiology-the cell | show 🗑
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the cell adapts | show 🗑
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show | necrosis-cant meet demands of the nucleus
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show | 1.regeneration-replace injured tissue w/normal tissue-integrity and func restored 2. scarring-injured cells replaced by connective tissue-integreaty restored not function,
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show | inflammation, proliferation and remodelling
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show | 1. hemostatis-immediate vasoconstriction, activate platelets, control blood loss, 2.Vascular response-vasodialtion, incrase cell permeability, plasa exit vessel enter damaged tissue(edema), 3.cellular respons WBC clear the area of bacteria and dead cells
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Proliferation phase | show 🗑
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Remodeling phase | show 🗑
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Acute inflammation | show 🗑
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acute inflammation 4+ | show 🗑
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Chronic inflammation | show 🗑
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Signs and Symptoms of Inflammation | show 🗑
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show | arachidonic-produces prostoglandins-basodilate &sensitize receptors to bradykinins& histamin-decrease p!threshold, increased sensiati vity to p!
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lipoxygenase pathway | show 🗑
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cycloxygenase COX pathway | show 🗑
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Non-Selective/traditional NSAIDs | show 🗑
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Selevtive(celebrex, vioxx, Bextra) | show 🗑
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NSAIDs | show 🗑
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Corticosteriord | show 🗑
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corticosteroid side effects | show 🗑
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show | treats-midle/mod p!, fever--dosage-tablets, capsules, chewAVLE, SUPPORISTORES-side effects increase risk for liver toxivity, overdose-does not inhibit platelet aggregation like NSAIDs
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show | treat-mod/sever p!, post-op, cancer--admin-oral, inj, rectal--side effects-drowsiness, euphoria, abuse, constipation--narcotics-oxycodone, demerol, opiates-morphone, codine
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show | treat-bacterial inf, admin-oral, IM, IV--side effects-allergic reaction, dependant on drug-interact w/ oral contraceptives-less effective, misuse has lead to MRSA
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show | inhibits synthesis of bacteria cell wall, works to kill invading bacteria
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show | keeps bacteria from reproducing, allowing the immune system time to kill bacteria-high doesse or in conjunction w/ other antibiotics can kill
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Antihistamines | show 🗑
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H1 antihistamines | show 🗑
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H2 antihistamines | show 🗑
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show | used to treat-nasal congestionw/ allergies, common cold, how-vasoconstirc blood vessels in nasal passage to help reduce swelling of mucosal membrane, admin-oral(sutafed), nasal spray Afrin-only use 305 days- rebond congestion),
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decongestant side effects | show 🗑
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show | used to treat-asthma, expand airways, relax bronchial spasm, admin-oral, inhaled(actquicker, fewer side effects) Side effects-side effects-tachycarda, increased BP, increased bloodsugar, nausea, vomit, nervousness, restlessness, diuretic
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Gastrointestinal drugs-antidiarrheals | show 🗑
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show | bulkform-fiber, swells when mixed w/h2o, stimlatesperistalsis-12-72 hrs, osmotic lax-draw h2o to intestinal lumen, increasae peristaltis 1-3 hrs, stimlant-increase bowelmotility, stomach cramps 6-10hrs, stool softeners-soften contents of bowel, prevention
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show | neurtalize stomach acid, used to treat peptic ulcer, heartburn, mild cases of GERD, take after meal, before bed, results:5-15 min, note:reduce absorption of other meds for 2 hrs
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Proton Pump inhibitors(PPI) | show 🗑
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show | antagonists to histamine(h2), D acid production, dose dependant on condition being treated
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show | used to treat-superficial(mucous membrane, skin hair, nailes), systemic-side effects:oral:nausea vomit, abp!, HA, topical:itching burning, skin irritation
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Fungicidals | show 🗑
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show | prevent cell prlication, allows immune system to manage infection
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show | prescription only, used to treat/reduce the duration/severity of: herpes virus, inluenza
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