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Nutrition - Vitamins

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show Liver, green leafy vegetables, yellow-orange vegetables, fruit & fortified foods  
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show Intestinal Lumen; Retinyl esters  
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What substance from Vitamin A is released from the intestinal epithelial cells into the blood?   show
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show RBP-retinol  
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show Retinol; Retinyl esters  
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show Vision, reproduction, immune function, cell proliferation, cell signaling,  
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What form of Vitamin A is used for vision?   show
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show Retinol; mediates lymphocyte survival and proliferation  
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What are the symptoms for Vitamin A deficiency?   show
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What are the diseases caused by Vitamin A deficiency?   show
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show Structural damage to the cornea and Bitot's spot  
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show Teratogenic effects, liver disease, dryness, erythema (redness of skin), scaling/peeling of skin, hair loss, nail problems, headache, nausea, vomitting, overgrowth of periosteal bone, and increase in bone fractures  
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What are the significant sources of Vitamin D?   show
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show Liver  
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Liver converts Vitamin D to what structure? Where does this structure travel to?   show
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show -1,25(OH)2D -Involved in calcium homeostasis, muscle and bone health, BP regulation, insulin production, prevention of heart disease and type 2 diabetes)  
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The prostate gland, breast, colon, lung, immune cells produce what form of Vitamin D? What does this form of Vitamin D do for the body?   show
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show Rickets; Disorganization & hypertrophy of chondrocytes at mineralization front  
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Deficiency of Vitamin D would lead to what disease in adults? Describe the disease.   show
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Toxicity of Vitamin D   show
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show -absorption and transport is similar to that of cholesterol absorption/transport -Absorption is initiated in the intestines where they are absorbed by the enteroscytes -Vitamin E and corresponding triglycerides are then incorporated into chylormicrons  
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show -The movement of Vitamin E throughout the lymphatic system is identical to that of cholesterol and fats. Once absorbed in the liver is incorporated into VLDLs or used to make water-soluble metabolites of vitamin E.  
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Describe the absorption of Vitamin E (part 3)   show
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show -protect membrane lipids and proteins from free radical damage -The tocopherols donate an e- to the free radical thus removing the free radical and protecting lipids & proteins from being oxidized  
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Other Vitamin E non-free radical activities   show
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show Oil seeds, salad dressings, mayonnaise, margarines, oils (sunflower/safflower), nuts, and various spreads are the highest sources of Vitamin E in our diet  
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What has animal studies shown us about Vitamin E deficiency?   show
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show -Decreased life span of RBC's -Deficiencies are rare, but often present in patients with lipoprotein deficiencies, lipid malabsorption syndromes, and fat malabsorption conditions -Vitamin E is inadequately transferred across the placenta  
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What do epidemiology studies say about Vitamin D Deficiency?   show
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Toxicity of Vitamin E   show
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Significant Sources of Vitamin K from diet   show
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show -Similar to fat absorption -transported in chylomicrons to the liver as a chylomicron remnant -found circulating in HDLs, LDLs, & VLDLs -phylloquinone is excreted primarily in the feces, but may be excreted in the urine  
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show -Secondary deficiency -normal "flora" bacteria (prod Vit K) is absent in newborns -Vit K is typically low in breast milk -Hypothrombinemia in newborns -commercial infant formula is formulated w/ Vit K -Mothers can increase vit K lvls in breast milk w  
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show -In newborns -Antibiotic consumption can induce vitamin K deficiency -Patients undergoing long term total parenteral nutrition -Malabsorption problems  
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show -Plasma/serum phylloquinone concentrations not typically used -Prothrombin time-an indirect test used to assess Vitamin K levels  
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Created by: jgrayson
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