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WVSOM - FA synthesis
WVSOM -- Fatty Acid Synthesis
|When does FA synthesis occur?
|When there are more calories ingested than are needed
|Beginning Product of FA synthesis
|Citrate converted into what two products in preparation for FA synthesis
|Oxaloacetate and Acetyl CoA
|Acetyl CoA goes to what
|3 Carbon compound needed for the immediate sgtarting material for FA synthesis
|What cofactor is needed in all carboxylases?
|Fate of oxaloacetate from citrate lyase reaction
|Oxaloacetate -> Malate -> Pyruvate
|Location of FA synthesis
|When is FA synthesis active
|Fed state assuming excess calories present
|FA synthesis Starting material
|NADPH Malonyl CoA Acetyl CoA
|FA Synthesis Products
|Process of FA synthesis
|Reduction of carbons/oxidation of NADPH (reverse B oxidation)
|Where do we get NADPH?
|Pentose Phosphate Pathway
|Fatty Acid Synthase
|large complex of enzymes that binds growing acyl chain and malony CoA in first round.
|Why is malonyl CoA used rather than acetyl coa?
|Fate of new synthesized FA
|activated to fatty acyl CoA for TG synthesis and incorporated into VLDL