RPE
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| What is the RPE? | show 🗑
|
||||
| show | 1.ABSORPTION of stray light to enhance visual acuity 2.PROTECTION against toxic and oxidative damage 3.FORMATION of the blood- retina- barrier 4.SELECTIVE TRANSPORT of substances to/from neural retina 5.ELIMINATION of metabolic waste 6. PROCESSING of vit
🗑
|
||||
| show | 4 to 6 million cells in a hexagonal pattern
🗑
|
||||
| What is the cell density of RPE? | show 🗑
|
||||
| show | they face ~30-40 photoreceptors. PHAGOCYTIZE shed discs of photoreceptor outer segments on a daily basis
🗑
|
||||
| show | pigmented epithelium of the ciliary body
🗑
|
||||
| show | apex- to- apex intimate relationship between APICAL OUTER SEGMENTS of the photoreceptors and the APICAL MICROVILLI of the RPE cells.
🗑
|
||||
| show | potential space seaparating the RPE from photoreceptor
🗑
|
||||
| show | APEX: inward (towards vitreous) BASAL: faces outward (towards schlera)
🗑
|
||||
| show | inner most layer of Bruch's membrane of choroid
🗑
|
||||
| show | extends numerous microvilli into the space between RPE from photoreceptors (subretinal space) that interlock with the rod outer segments
🗑
|
||||
| show | located between the apical membrane and photoreceptors. it keeps the APICAL MICROVILLI and PHOTORECEPTOR OUTER SEGMENTS bound together, but no junctional attachments occur. it also exchanges metabolites and interactions between the photoreceptors and RPE
🗑
|
||||
| show | they phagocytize the discs of the photoreceptor outer segments and can be seen in the cytoplasm of the RPE as phagosomes
🗑
|
||||
| show | they are gradually digested by intracellular enxymes and their end products are 1. deposited on Bruch's membrane (drusen) or 2. stay within the cell as lipofuscin grandues
🗑
|
||||
| Does the lipofuscin grandules increase or decrease with age? | show 🗑
|
||||
| show | RODS: early morning CONES: end of the day
🗑
|
||||
| show | once every 8-13 days
🗑
|
||||
| show | in the APICAL membrane: NA-K-ATPase. but other transport epithelia have this system in the basolateral PM. this system helps regulate fluid fluzes that contribute to the adhesion of neurosensory retina to the RPE
🗑
|
||||
| What is special about the lateral membrane of RPE? | show 🗑
|
||||
| show | highly complex with infoldings to about 1micrometer into the cytoplasm of the cell. the infolding incrase the SA of the cell for ABSORPTION and SECRETION (transport function)
🗑
|
||||
| Where does drusen deposit? | show 🗑
|
||||
| The deposits of metabolic waste on Bruch's membrane make it? | show 🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
dyoungee
Popular Anatomy sets