Final study guide
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Teratogen | show 🗑
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| show | pregnant women
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| FDA Guidelines A | show 🗑
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| FDA Guidelines B | show 🗑
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| show | Animal studies show risk but there are no human studies OR there are no studies in humans or laboratory animals
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| show | Evidence of human risk but benefits may make use acceptable
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| show | Studies show risk; risk of use clearly outweighs any possible benefit
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| Dangers of relying on FDA Pregnancy Categories | show 🗑
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| What do you need to utilize other resources? | show 🗑
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| show | mg of folic acid prior to and during pregnancy
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| show | 1. Route 2. Timing (critical period) 3. Dosage 4. Duration 5. genotype of fetus
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| Background risk for a baby to have a congenital anomaly is | show 🗑
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| Lithium | show 🗑
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| show | Depakote, Dilatin, Phenobarbatal
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| Chemotherapeutic agents | show 🗑
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| show | Critical period of exposure: Second and third trimester IUGR, Hypocalcaria manifested by very large anterior fontanel, persistent PDA, renal tubular dysplasia leading to oligohydramnios and Potter's sequence
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| show | reduce uterine blood flow, leading to decreased placental perfusion and severe fetal hypotension. Block fetal ACE activity, thereby affecting systemic and renal hemodynamics in the fetus
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| show | 1. Malformations 2. OB complications 3. hemorrhage and other problems in the newborn, 4 developmental delays 5. behaviorial problems
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| show | 1. Broad depressed nasal bridge 2. short nose with anteverted nares 3. Long philtrum 4. Maxillary hypoplasia 5. fingernail hypoplasia
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| show | Masculinization of the female fetus, dose-dependent and critical period 8-13 weeks (labial fusion) later in pregnancy (clitoral hypertrophy)
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| show | up to 20 weeks gestation, highest risk for adenocarcinomas between weeks 10 and 13
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| show | Antley-Bixler like phenotype, Pattern of malformations: brachycephaly, craniosynostosis, proptosis, low nasal brdige, cleft palate, femoral bowing, thin ribs and long bones' joint contractures, congenital heart defects
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| Retinoids | show 🗑
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| Critical period for isotretinoin/Retinoids | show 🗑
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| Tetracycline | show 🗑
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| Streptomycin | show 🗑
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| show | Phocomelia, amelia, heart defects, renal and genitourinary anomalies, oral clefts, anomalies of the eyes and external ears
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| Warfarin | show 🗑
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| Critical period for NTDs | show 🗑
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| Critical period for MR | show 🗑
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| show | 32-38 weeks
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| Critical period for TA, ASD, and VSD | show 🗑
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| show | 6 2/3rd through 8 weeks
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| show | 4 weeks to 6 weeks
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| Less critical period for upper limb | show 🗑
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| show | 6 weeks to 9 weeks
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| Critical period for cleft lip | show 🗑
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| less critical period for upper lip | show 🗑
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| Low-set malformed ears and deafness | show 🗑
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| less critical period ears | show 🗑
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| Critical period for microhthalmia, cataracts and glaucoma | show 🗑
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| show | weeks 8 through birth
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| critical period for enamal hypoplasia and staining | show 🗑
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| less critical period for teeth | show 🗑
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| show | weeks 7 and 8
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| show | week 9
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| critical period for masculinization of female genitalia | show 🗑
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| less critical period for external genitalia | show 🗑
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| What drugs are associated with clefting? | show 🗑
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| Chemotherapeutic agents critical period | show 🗑
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| ACE Inhibitors critical period | show 🗑
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| show | 8-13 weeks gestation
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Created by:
KChatham
Popular Genetics sets