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Nightingale Pathophysiology Summer 2022 Midterm Review

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Term
Definition
The nurse is caring for a patient with a genetic disease that is transmitted through autosomal recessive inheritance. What is the likely diagnosis?   CF  
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Adaptive cellular mechanisms function to:   Protect cells from injury  
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If a patient has liquefactive necrosis, which organ should the nurse assess first?   Brain  
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The nurse is in the genetics clinic describing a disease that leads to progressive dementia in middle to late adulthood...   Huntingtons  
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The triplet of base pairs necessary to code for a specific amino acid is:   Codon  
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The outward manifestation of a disease, often influenced by both genes and the environment is called the disease   Phenotype  
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The condition that occurs when a zygote is missing in each cell is referred to as:   a "monosomy"  
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The process by which RNA is formed from DNA for protein synthesis:   Transcription  
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The somatic cell that contains a multiple of 23 chromosomes is called:   A euploid cell  
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What is the chief function of ribosomes   Protein synthesis  
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A disease that results in lipids in the nerve cells of the brain   Tay-Sachs  
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Cellular atrophy is:   A decrease in cell size  
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The process by which cells program themselves to die:   Apoptosis  
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What causes metaplasia in humans   Cell injury from noxious stimuli  
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The postmortem decrease in a patient's body temperature will be documented as:   Algor mortis  
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Dysplasia is characterized by abnormal changes in:   Cell Secretions  
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Clastogens are agents that cause:   Chromosomal breakage  
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When a patient has an extreme laceration (with a flap) how is that documented?   Avulsion  
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A patient with combined immunodeficiency lacks   T and B lymphocytes  
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When assessing a patient with SLE, you should expect to identify   Arthralgia, anemia, and rash  
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Your patient is having a reaction to a bee sting. What type if hypersensitivity is this?   Type I  
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The major phagocytic cells in inflammation are:   Neutrophils and macrophages  
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What is the role of plasmin in the inflammatory response cycle?   Controls clotting by breaking down fibrin  
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Among the many innate defenses the body has to pathogens, the first line of defense is:   Skin and mucous membranes  
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Which substance is released during a viral infection and signals neighboring cells to enhance viral defenses?   Interferon  
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What term is used to describe the process of endocytosis   Engulfment  
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DiGeorge syndrome is characterized by absence or underdevelopment of which organ?   Thymus  
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You are planning a community event about systematic lupus erythematosus. To which population should your teaching be primarily focused?   Women 20-40 years old  
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The most common symptom reported associated with cancer is:   Fatigue  
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The retinoblastoma gene is what type of gene   Tumor-suppressor  
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A process in which a piece of one chromosome is moved to another chromosome is:   Translocation  
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What term is used to describe cancer that extends to organs or tissues different from the site of origin?   Metastasis  
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What is the leading cause of death in developed countries?   Cancer  
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What would you expect to occur when a patients cancer is caused by mutations of a proto-oncogene?   Increased cell division  
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A patient is experiencing leukopenia from cancer and chemotherapy treatment. Which condition should you assess for in this patient?   Infection  
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Malignant tumors have a tendency to:   Invade surrounding tissues and metastasize  
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For metastasis to occur, tumors must be capable of:   Surviving in the bloodstream  
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The development in sensory and motor symptoms in MS is caused by:   Immunologic and inflammatory demyelination of CNS neurons  
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Subdural hematomas:   Bleed between the dura matter and the brain  
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Autonomic hyperreflexia is caused by:   Stimulation of sensory/pain receptors below the level of the spinal cord lesion  
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What usually causes encephalitis   Viral infection  
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Most forms of focal brain injury are associated with increased:   Brain swelling  
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ALS is caused by:   Degeneration of upper and lower motor neurons  
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A patient has a spinal cord tumor that originated within neural tissues. What is this called?   Intramedullary  
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A sign associated with classic cerebral concussion is:   Loss of consciousness  
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Your patient has Guillan-BarrĂ©. During the health history you should ask about:   Resp. or GI viral infections  
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Cerebral Thrombosis most often develops from:   Atherosclerosis and inflammatory disease process  
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Which intervertebral disks should be assessed first for herniation?   L4-S1  
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Your patient's head hit the steering wheel during an MVC. Which part of the brain received the coup injury   Frontal  
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What type of injury will the nurse prepare to care for with a diffuse brain injury?   Concussion  
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A patient has a recent spinal cord injury. Which term should the nurse use to describe the loss of reflex function below the level of injury?   Spinal shock  
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Your patient has HIV and painful burning dysesthesias, especially in the extremities. What condition will you document?   HIV neuropathy  
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During assessment of a patient with meningitis, you want to test for nuchal rigidity. What do you perform?   Kernig  
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During a myasthenic or cholinergic crisis, a patient is in danger of:   Resp. arrest  
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Irritative syndromes involve:   Compressive symptoms plus radicular pain and paresthesias  
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A herniated disk allows the nucleus pulposus to:   Extrude and compress the nerve root.  
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The eukaryotic cell consists of three general components:   plasma membrane, cytoplasm, intracellular organelles  
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An inherited alteration of genetic material is called:   Mutation  
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Reversible replacement of one mature cell type by another less matured cell type is:   Metaplasia  
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A problem of fluid distribution that results in accumulation of fluid within interstitial spaces is:   Edema  
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Waterbalance is regulated by:   Sensation of thirst and ADH  
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What is regulated by the kidney, aldosterone, insulin secretion, and changes in pH   Potassium balance  
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The second line of defense is:   Inflammatory response  
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What are molecules that bind and react with components of the immune response, such as antibodies and receptors on T and B cells   Antigens  
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What enters host cells and uses the metabolic processes of host cells to proliferate and cause disease?   Viruses  
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A propensity to unusual or recurrent severe infections is a hallmark for:   Immunodeficiency I  
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