310 Midterm 3
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| show | science that deals with the fate of drugs in the body and their actions on the body
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| drug | show 🗑
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| show | by DEA, schedule I to IV
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| show | prescription
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| show | extracts are uncontrolled, but as soon as the active chemical is isolated, it is classified as a drug and becomes controlled
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| show | study of actions of drugs on the body
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| show | quantitative description of drug disposition
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| drug disposition | show 🗑
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| drug disposition curve | show 🗑
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| show | absorbed, distributed, eliminated
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| show | enteral, parenteral
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| show | enteral: through alimentary canal
parenteral: everywhere else
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| venous samplings/vein sticks | show 🗑
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| extra label drug use | show 🗑
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| show | continuous, fenestrated, or discontinuous
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| show | layer of lipophilic cells surrounding capillaries
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| fat stores of the body | show 🗑
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| show | water-loving vs. fat-loving
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| show | bound to albumin, free drugs get absorbed quicker
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| biotransformed | show 🗑
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| specific receptors/target cells | show 🗑
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| show | where the drug takes effect
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| receptor pull/affinity | show 🗑
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| show | in general, 10 half lives and a drug is considered eliminated
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| show | first time the blood passes through the liver, 100% of it is broken down
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| show | how quickly you want the drug to work vs. route of administration
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| drug conjugation | show 🗑
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| half-life | show 🗑
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| quality assurance issues | show 🗑
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| quantitative vs. qualitative dose-response curves | show 🗑
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| show | how much of a drug is needed to get the desired response
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| show | amounts of drugs needed to achieve same response
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| show | effective dose in which 50% of the population responds
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| show | toxic dose, 50% of population gets sick
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| show | TD50/ED50
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| show | lethal dose, 50% of population dies
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| AD50 | show 🗑
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| show | therapeutic objective, physical properties of drug, lipophilic/hydrophilic, quality assurance issues, cost
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| kidney | show 🗑
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| show | secrete hormones
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| hilus | show 🗑
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| micturition | show 🗑
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| sphincter | show 🗑
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| metanephric nephron anatomy | show 🗑
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| show | first capillary bed
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| PTC | show 🗑
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| descending limb | show 🗑
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| ascending limb | show 🗑
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| loop of Henle | show 🗑
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| show | where aldosterone works, can pump so much sodium that osmotically it can become more dilute than normal interstitium
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| show | receives the urine from many distal tubules
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| show | filters/cleans the plasma
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| show | 20-25% goes to kidney
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| vasa recta | show 🗑
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| portal system | show 🗑
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| show | glomerulus + Bowman's capsule
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| show | filters and cleans plasma, 20-25% filtered out into Bowman's capsule
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| show | active transport of toxins directly into urine from PTC, reabsorption
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| show | steroid hormone from adrenal cortex, mineral corticoid
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| osmolarity/milliosmole | show 🗑
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| cortical vs. juxtamedullary nephrons | show 🗑
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| show | waste products
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| salt gland | show 🗑
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| show | if blood volume is too high, urine volume increases to compensate and vice versa
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| juxtaglomerular apparatus | show 🗑
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| show | macula densa cells
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| show | monitor if kidney isn't filtering enough blood and if the osmolarity of blood is correct
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| show | how much fluid is filtered out of glomerulus into Bowman's capsule
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| renin-angiotensin system | show 🗑
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| show | angiotensin converting enzyme
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| angiotensinogen | show 🗑
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| angiotensin | show 🗑
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| angiotensin activator | show 🗑
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| show | entire body experiences vasoconstriction
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| GFR homeostasis/disturbance/recovery | show 🗑
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| show | steroid hormone from adrenal cortex
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| adrenal cortex | show 🗑
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| zona glomerulosa | show 🗑
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| show | reabsorbed in proximal tubule
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| blood-born | show 🗑
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| diuresis | show 🗑
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| high blood pressure | show 🗑
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| show | decreases urine volume, affects collecting duct of nephrons, allows for very concentrated urine
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| hypothalamus/posterior pituitary | show 🗑
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| range of urine osmolarities | show 🗑
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| show | hypovolemic: loss of blood volume
osmotic: high osmolarity
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| show | drinking and eating provide water, kidney conserves water so output=intake
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| show | maintain homeostasis, support cell growth, coordinate development/reproduction, facilitate responses to external stimuli
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| show | stimulates neighboring cells
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| show | stimulates self only
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| show | stimulates cells far away
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| endocrine/ductless glands | show 🗑
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| show | a chemical made in one part of the body that becomes blood born, travels to another part of the body to affect a target cell
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| show | has receptors for hormone
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| show | controls pituitary gland
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| show | connects hypothalamus and pituitary
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| show | outgrowth of base of brain, forms posterior pituitary
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| posterior pituitary/neurohypophysis | show 🗑
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| anterior pituitary/adenohypophysis | show 🗑
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| show | stimulates release of growth hormone
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| growth hormone/GH/somatotrophin | show 🗑
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| IGF-1/somatomedin | show 🗑
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| somatostatin | show 🗑
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| bST vs. hGH | show 🗑
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| gigantism | show 🗑
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| show | control amount of initial stimulant produced
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| thyroid | show 🗑
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| isthmus | show 🗑
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| left and right lobe | show 🗑
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| thyroglobulin | show 🗑
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| colloid | show 🗑
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| follicle | show 🗑
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| MIT | show 🗑
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| show | diiodotyrosine
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| triiodothyronine | show 🗑
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| show | T4, DIT + DIT
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| show | thyrotropin releasing hormone, released by hypothalamus, stimulates release of TSH by anterior pituitary
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| TSH | show 🗑
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| show | T3, T4
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| hypothalamo-pituitary-organ axis | show 🗑
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| show | negative feedback on hypothalamus (causes it to release less TRH)
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| hypo/hyperthyroidism | show 🗑
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| show | autoimmune disorder, most common cause of hyperthyroidism
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| show | swelling of the skin, caused by hypothyroidism
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| goiter | show 🗑
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| goitrogens | show 🗑
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| exopthalamos | show 🗑
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| feedback | show 🗑
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| show | released when calcium in blood is low
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| effect of PTH | show 🗑
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| show | caused by parathyroid hormone when Ca in blood is too low to help absorb Ca from intestine
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| show | concentrates urine
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| show | make calcitonin, controlled by Ca in blood, oppose PTH, released when Ca in blood is too high
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| calcitonin | show 🗑
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| show | corticotrophic releasing hormone made by hypothalamus, causes production of ACTH
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| ACTH | show 🗑
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| show | steroid from adrenal cortex affecting glucose
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| cortisol | show 🗑
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| show | adrenal steroids
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| pancreatic islets/Islets of Langerhans | show 🗑
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| show | alpha: secrete glucagon
beta: secrete insulin
work opposite each other
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| glucagon | show 🗑
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| show | necessary for sugar to get inside a cell, allows body cells to take in circulating glucose, works opposite glucagon
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| control of insulin | show 🗑
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| diabetes | show 🗑
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| hypo/hyperglycemia | show 🗑
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| ketotic/ketosis | show 🗑
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| peripheral circulation/capillary health | show 🗑
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| A1C | show 🗑
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Created by:
hbrandt
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