310 Midterm 3
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| show | science that deals with the fate of drugs in the body and their actions on the body
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| drug | show 🗑
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| show | by DEA, schedule I to IV
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| show | prescription
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| show | extracts are uncontrolled, but as soon as the active chemical is isolated, it is classified as a drug and becomes controlled
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| show | study of actions of drugs on the body
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| pharmacokinetics | show 🗑
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| drug disposition | show 🗑
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| show | graph to show drug disposition
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| show | absorbed, distributed, eliminated
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| routes of drug administration | show 🗑
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| enteral vs. parenteral | show 🗑
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| venous samplings/vein sticks | show 🗑
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| show | using a drug other than how it is indicated on the label
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| capillary barriers | show 🗑
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| show | layer of lipophilic cells surrounding capillaries
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| fat stores of the body | show 🗑
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| hydrophilic vs. lipophilic | show 🗑
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| show | bound to albumin, free drugs get absorbed quicker
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| show | way in which drug gets eliminated
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| specific receptors/target cells | show 🗑
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| show | where the drug takes effect
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| receptor pull/affinity | show 🗑
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| show | in general, 10 half lives and a drug is considered eliminated
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| show | first time the blood passes through the liver, 100% of it is broken down
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| show | how quickly you want the drug to work vs. route of administration
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| show | bound to a sugar molecule
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| show | amount of time it takes for 1/2 the drug to be broken down
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| show | in food animals, quality of meat
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| quantitative vs. qualitative dose-response curves | show 🗑
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| show | how much of a drug is needed to get the desired response
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| equipotent doses | show 🗑
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| effective dose 50 | show 🗑
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| show | toxic dose, 50% of population gets sick
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| show | TD50/ED50
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| LD50 | show 🗑
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| show | anesthetic dose, 50% of population goes under anesthesia
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| show | therapeutic objective, physical properties of drug, lipophilic/hydrophilic, quality assurance issues, cost
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| kidney | show 🗑
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| adrenal gland/supra adrenals | show 🗑
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| show | ureter/renal artery/renal vein enter into kidney
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| show | urination
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| show | holds bladder closed
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| metanephric nephron anatomy | show 🗑
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| show | first capillary bed
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| PTC | show 🗑
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| show | thin walled
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| ascending limb | show 🗑
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| show | allows last 20-40% of water to not be lost in urine
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| show | where aldosterone works, can pump so much sodium that osmotically it can become more dilute than normal interstitium
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| collecting duct | show 🗑
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| Bowman's capsule | show 🗑
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| show | 20-25% goes to kidney
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| show | 1-2% of PTC bed that forms a loop around the loop of Henle
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| portal system | show 🗑
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| renal corpuscle | show 🗑
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| glomerulus and filtration | show 🗑
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| show | active transport of toxins directly into urine from PTC, reabsorption
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| show | steroid hormone from adrenal cortex, mineral corticoid
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| show | saltiness of blood
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| cortical vs. juxtamedullary nephrons | show 🗑
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| ammonia/urea/uric acid | show 🗑
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| show | concentration of salt out of it is greater than sea water, found in sea birds
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| control of blood volume | show 🗑
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| show | source of renin
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| juxtaglomerular cells | show 🗑
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| macula densa monitor | show 🗑
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| show | how much fluid is filtered out of glomerulus into Bowman's capsule
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| show | renin converts angiotensinogen into angiotensin
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| show | angiotensin converting enzyme
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| angiotensinogen | show 🗑
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| show | circulation, vasoconstriction, renal blood flow increases, constriction of efferent artery, increase in glomerular filtration
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| angiotensin activator | show 🗑
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| show | entire body experiences vasoconstriction
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| show | disturbance: GFR goes down, renin released, angiotensin activated, BP and BV increase
recovery: restored homeostasis, GFR increases
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| aldosterone/mineral corticoid | show 🗑
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| adrenal cortex | show 🗑
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| show | outer layer of adrenal cortex, makes aldosterone
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| sodium reabsorption | show 🗑
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| show | enters into circulatory system from endocrine system
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| diuresis | show 🗑
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| high blood pressure | show 🗑
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| show | decreases urine volume, affects collecting duct of nephrons, allows for very concentrated urine
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| hypothalamus/posterior pituitary | show 🗑
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| range of urine osmolarities | show 🗑
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| hypovolemic vs. osmotic thirst | show 🗑
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| show | drinking and eating provide water, kidney conserves water so output=intake
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| show | maintain homeostasis, support cell growth, coordinate development/reproduction, facilitate responses to external stimuli
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| show | stimulates neighboring cells
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| autocrine | show 🗑
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| show | stimulates cells far away
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| show | invading epithelia become a deep gland or get isolated/pinched off
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| hormone | show 🗑
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| receptor/target cell | show 🗑
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| hypothalamus | show 🗑
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| stalk | show 🗑
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| show | outgrowth of base of brain, forms posterior pituitary
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| posterior pituitary/neurohypophysis | show 🗑
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| anterior pituitary/adenohypophysis | show 🗑
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| growth hormone releasing hormone | show 🗑
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| show | causes fat to be broken down
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| show | bone growth, muscle development
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| somatostatin | show 🗑
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| bST vs. hGH | show 🗑
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| show | too much growth hormone released
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| controlling hormones/factors | show 🗑
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| show | composed of epithelial cells, 2 lobes, made of fluid filled follicles, releases T3 and T4
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| show | connects two lobes of thyroid
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| left and right lobe | show 🗑
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| thyroglobulin | show 🗑
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| show | fluid filling follicles
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| show | small sac or vesicle, filled with fluid
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| show | monoiodotyrosine
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| show | diiodotyrosine
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| triiodothyronine | show 🗑
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| tetraiodothyronine | show 🗑
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| show | thyrotropin releasing hormone, released by hypothalamus, stimulates release of TSH by anterior pituitary
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| TSH | show 🗑
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| metabolic hormones | show 🗑
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| hypothalamo-pituitary-organ axis | show 🗑
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| effect of T3 and T4 | show 🗑
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| hypo/hyperthyroidism | show 🗑
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| show | autoimmune disorder, most common cause of hyperthyroidism
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| myxedema | show 🗑
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| goiter | show 🗑
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| show | drugs or feed that interferes with thyroxin production
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| exopthalamos | show 🗑
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| feedback | show 🗑
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| show | released when calcium in blood is low
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| show | calcium is reabsorbed into kidney, calcium comes out of bone and into blood, kidney activates vitamin D
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| vitamin D activation | show 🗑
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| show | concentrates urine
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| show | make calcitonin, controlled by Ca in blood, oppose PTH, released when Ca in blood is too high
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| calcitonin | show 🗑
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| show | corticotrophic releasing hormone made by hypothalamus, causes production of ACTH
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| ACTH | show 🗑
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| show | steroid from adrenal cortex affecting glucose
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| show | most common adrenal steroid, anti-inflammatory, stress hormone, inhibits fertility, stimulates fetal lung maturation, increase glucose levels in blood, induces parturition
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| show | adrenal steroids
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| show | endocrine portion of pancreas, secrete alpha and beta cells
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| alpha/beta cells | show 🗑
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| show | acts on liver to stimulate glucose production and release, causes fat breakdown, rises when glucose falls
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| insulin | show 🗑
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| control of insulin | show 🗑
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| show | inability to bind glucose
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| show | hypo: lack of glucose
hyper: too much glucose, leads to hyperosmolarity
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| show | decreased blood pH
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| peripheral circulation/capillary health | show 🗑
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| A1C | show 🗑
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Created by:
hbrandt
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