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A&P II - Human Blood

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Question
Answer
show 1) transport nutrients, gases, and wastes, 2) regulates pH levels and temperature, 3) Restricts fluid loss, 4) Defends Body Against Toxins & Pathogens  
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blood is what kind of tissue   show
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show blood is 5 times more viscous than water  
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what are the components of blood   show
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out of all the three main elements that make up the blood, which one makes up a majority of blood volume   show
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name the three types of proteins in the blood that are part of fluid matrix   show
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where are the plasma proteins mostly produced   show
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out of the three plasma proteins (fibrinogen/albumin/globulin) is the most abundant   show
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what is the main plasma protein that contributes to osmolarity and osmotic pressure in capillaries   show
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what are the plasma proteins that become antibodies (Immunoglobulins, Ig)   show
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where is all albumin made?   show
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why is fibrogen an important protein in blood plasma   show
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show fibrogen become fibrin during the clotting process  
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what leaves a serum during the clotting process   show
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show fibrogen (after it becomes fibrin) removes Ca++ during the clotting process  
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plasma and serum (can be used interchangably/are different things)   show
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show plasma expanders temporarily increases blood volume  
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what is an ideal time to use a plasma expander   show
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where is fibrinogen synthesized?   show
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show if the liver is not functioning, plasma proteins like albumin and fibrinogen are not synthesized  
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show there will be clotting disorders because necessary proteins like fibrinogen are not produces  
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show there will be problems with osmolarity and osmotic pressure, if the liver fails to produce enough albumin  
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what is hematopoesis   show
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platelets are (cell fragments/whole cells)   show
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what is the process called that synthesizes Red Blood Cells   show
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show red blood cells contain hemoglobin  
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show hemoglobin is the protein/molecule that transports respiratory gases  
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what is the most abundant formed element in blood   show
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show whole blood  
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show water  
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show formed elements abundance  
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show red bone marrow  
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red blood cell production is regulated by the hormone _____________________.   show
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the average life span of a red blood cell is   show
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show more bilirubin appears in the plasma  
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show carry dissolved gases  
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show four iron atoms  
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show both ABO and R blood groups  
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show neutrophils  
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the function of platelets is to assist in the processes called   show
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show cytoplasmic fragments of large cells  
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show vitamin K  
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show 4 (four)  
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a decrease in the oxygen-carrying ability of the blood, for any reason, is a condition known as   show
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show positive  
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what is another term for formed elements   show
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show hematocrit makes up 45% and plasma makes up 55% of blood volume  
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hematocrit includes (PICK ONE: Red Blood Cells, White Blood Cells, Platelets, All the above)   show
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show the process in which formed elements are developed  
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what is the process that forms Red Blood cells   show
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show red blood cells  
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which molecule in blood has a sole function to transport respiratory gases   show
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show 4.5-6.3  
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about how many RBC's are there in women (per microLiter)   show
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what is a blood draw   show
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what vein is commonly used when drawing blood for analysis? (looking from the outside of the body, where is this vessel generally located)   show
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show venipuncture  
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give three reasons why veins are the ideal location for blood draw   show
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what are some alternative locations for blood draws if the antecubital region is unavailable   show
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show to test levels of blood gases, indicates lung function  
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show 1) plasma (yellow hue) contains plasma proteins, electrolytes, and other dissolved elements, 2) buffy coat, includes white blood cells and platelets, 3) Red blood cells only  
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show it is the red blood cell layer and the buffy coat layer  
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what does it mean if the buffy coat increases in size   show
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how does dehydration affect the blood   show
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how does an increase in erythropoietin affect the   show
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with internal bleeding, what happens to formed element volume   show
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when there are problems with RBC formation, what happens to the volume of hematocrit   show
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what would you call a decrease in the number of reticulocytes   show
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a hypo-mean corpuscular volume is   show
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show increased RBC/Hemoglobin/Hematocrit counts  
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what is reticulosis   show
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what is erythrocytosis   show
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what is hypochromic   show
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if a person is macrocytotic it means that   show
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if a person is hyperchromic it means that   show
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generally speaking, what is the average pH of blood   show
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show the red blood cell  
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show spectrin proteins give RBC's their shape and flexibility  
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what is the special shape that give RBC's their special features   show
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show spectrin protein creates a mesh work in the plasma membrane  
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what are the three major advantages of the shape of red blood cells   show
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why is it important to have a large surface area in red blood cells   show
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what is rouleaux   show
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why is it important for RBC's to have the ability to stack in small vessels   show
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during RBC development, it (keeps/looses) its organelles   show
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show nucleus and mitochonria  
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why do RBC's have relatively short life spans   show
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why is it important that an RBC does not have mitochondria   show
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show RBC obtain energy from anaerobic metabolism, so they do not steal O2 from Hemoglobin during transport AND because they do not have mitochondria  
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in the lungs (or other locations where the O2 concentration is high), what happens to the balance of the oxyhemoglobin chemical equation   show
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show heme gives hemoglobin it's red color  
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show globin is the protein that gives hemoglobin its shape  
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what are the names of the four chains that make up the hemoglobin structure   show
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show hemoglobin fits one oxygen molecule per chain  
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show myoglobin  
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show iron (specifically Fe2+)  
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oxygen attaches to (Fe2+/Fe4+)   show
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what part of the hemoglobin molecule has iron included in the structure   show
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the interaction between Iron and Oxygen is very (strong/weak)   show
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what is deoxyhemoglobin   show
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in peripheral tissues (where oxygen is low) which way does the oxyhemoglobin chemical equation equilibrium favor   show
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how does fetal hemoglobin differ from adult hemoglobin   show
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(fetal/adult) hemoglobin forms stronger bonds with oxygen   show
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when does fetal hemoglobin become adult hemoglobin   show
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what is carboxyhemoglobin   show
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why is carbon monoxide so dangerous   show
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how is sickle cell anemia generally treated   show
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what is sickle cell anemia   show
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show the HbO2 equation favors the left  
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what is the main problem with anemia   show
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show weakness, lethargy, and confusion (if the brain is affected)  
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show RBC plasma membrane ruptures at the end of life  
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what happens to an RBC after its membrane has ruptured   show
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what is erythropoiesis   show
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what are the two main stimulants for erythropoiesis   show
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show red blood cells appear during 3rd week of pregnancy  
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during the first 8 weeks of pregnancy, where does the formation of RBC's start   show
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show liver, spleen, thymus, and bone marrow  
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show after the 1st 8 weeks of pregnancy  
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between 2-5 months of pregnancy, where is the primary location for erythropoiesis   show
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show myeloid tissue of the red bone marrow  
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what is yellow bone marrow   show
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show yellow marrow CAN transition to red marrow  
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show hemoblasts (or hematopoietic stem cells)  
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what are the two types of daughter cells that can be produced after hematopoietic stem cells divide   show
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what types of blood cells are formed from myeloid stem cells   show
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what types of blood cells are formed from lymphoid stem cells   show
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how many stages are in RBC production   show
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show proerytheroblast  
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show reticulocyte  
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how long do recticulocytes stay in the red bone marrow prior to release   show
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when reticulocytes are released in to blood stream they (are/are not) fully mature RBC's   show
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what happens in to the reticulocyte after it has been released from red bone marrow (three things happen)   show
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what happens when there are lots of reticulocytes and not enough RBC's   show
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erythropoietin (is/is not) a banned substance for athletes   show
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show doping for athletes and treatment of kidney disease  
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what are the three situations in which kidneys release EPO   show
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show an autoimmune disease where intrinsic factor is destroyed  
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why is intrinsic factor so important   show
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show stomach  
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show Vitamin B-12 IS NOT destroyed, intrinsic factor is destroyed  
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what are the two main effects of EPO   show
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show can put a strain on the heart of healthy individuals because of increased blood volume  
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show anemia CAN result from prolonged blood loss  
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what are three major nutrients needed for RBC formation that cannot be made inside the body   show
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what is the source of vitamin b-12   show
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what is the effect of gastric reduction on RBC formation   show
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what are the three things that hemoglobin is broken down to at RBC are separated into at the end of their life   show
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what part of hemoglobin eventually becomes bilirubin   show
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show through the bile (from gall bladder)  
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show excess bilirubin is found in the blood plasma and gives skin and eye jaundice color  
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what is the name of the molecule that gives the skin it's yellow pigment color during jaundice   show
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what WBC assists with the hemoglobin recycling   show
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show in the spleen  
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what is the substance from recycled hemoglobin that combines with the protein transferrin   show
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show they are broken down into their respective amino acids which are recycled by the body to form new proteins  
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what is hemoglobinuria   show
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what is hematouria   show
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show when blood vessels in kidneys have been damaged  
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show 1) after a person has moved up to the mountains, 2) after doping, 3) chronic smoking and their body has produced more RBC  
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why can polycythemia be potentially dangerous   show
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show a type of cancer that produces too many RBC's  
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before becoming bilirubin, heme from recycled hemoglobin becomes _____________________   show
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what protein does bilirubin combine with prior to being excreted in bile   show
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show urobilinogens (urobilins when exposed to oxygen) and stercobilinogens (stercobilins when exposed to oxygen)  
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show it is reabsorbed by the body  
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show urobilinogens are excreted through the urine  
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show leaves via stool  
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show ferritin and hemosiderin  
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generally speaking, anemia is more of a (symptom/disease)   show
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show anemia  
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what are three main causes for anemia   show
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show antigens  
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what are surface antigens   show
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show surface antigens  
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what type of antigen are used to help with blood typing   show
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show the presence (or absence) of different surface antigens  
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name the for ABO blood types   show
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show electrolytes, nutrients, and organic wastes  
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show ferritin and hemosiderin  
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the process of hemostasis include five phases. what are the correct order of phases as they occur after injury?   show
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how is it that liver disorders can alter the composition and functional properties of the blood   show
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show hemoglobin molecules are excreted via the kidneys  
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on average, 1 microliter of blood contains _____________________ erythrocytes   show
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If. agglutinogen B meets with agglutinin anti-A, what is the results?   show
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show hemocytoblasts  
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show erythrocytes  
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In the first pregnancy of an Rh-negative mother with an Rh-positive child , why are there usually NO symptoms or erythroblastosis fetalis.   show
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the number of eosinophils increase dramatically during _____________________________   show
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show lymphocytes  
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show activation of the proenzyme plasminogen, which indicates the production of plasmin  
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show a breakdown of the common pathway, inactivating the clotting system  
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show sickle cell anemia  
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Jessica has just moved to Yellowstone Country, Montana from San Diego, California. What condition is she experiencing no that is stimulating the production of erythropoietin and, consequently more red blood cells   show
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which white blood cell attacks and digests bacteria marked with its complement   show
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which white blood cell releases histamine and heparin, when stimulated   show
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show eosinophils  
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what white blood cell is responsible for cell-mediated (or humoral) immunity   show
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show monocytes  
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which blood type has surface antigen A and anti-B antibodies   show
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which blood type has surface antigen B and anti-A antibodies   show
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which blood type has surface antigens A and B and no antibodies   show
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show Type O blood has no surface antigens, anti-A and anti-B antibodies  
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which blood type has Rh surface antigen, and no antibodies   show
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show 1) hemocytoblast, 2) proerythroblast, 3) normoblast, 4) reticulocyte, 5) erythrocyte  
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show adult female would normally have 4-5 liters of blood  
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show immunoglobin  
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show fibrinogen  
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show albumin does not transport iron  
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which blood cells are the most abundant (erythrocytes/neutrophils/platelets/monocytes)   show
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show reticulocytes account for about 1%  
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what is the range of normal hematocrit   show
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it is an illegal practice for Olympic competitors to receive doses of which hormone, which stimulates the production of red blood cells   show
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show Rh-negative woman, with an Rh-positive man  
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which white blood cell is also known as a polymorph   show
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During an infection, the white blood cell count may rise, a condition known as   show
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bleeding along the digestive tract and within the skin is symptomatic of _____________________   show
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show thrombocytosis  
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syneresis refers to the process of ________________   show
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what type of surface antigen does Type A have   show
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show Type B blood has type B surface antigen  
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what type of surface antigen does Type AB have   show
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show Type O blood has no surface antigen  
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show Type Rh positive blood has Rh surface antigen (Rh factor)  
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what type of surface antigen does the Rh negative have   show
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show agglutinogens are the surface antigens on Red Blood Cells  
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show agglutinogens are ignored by the immune system and help identify read blood cells as "self"  
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show agglutinins are antibodies in blood plasma  
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what attacks antigens on "foreign" RBCs causing the blood to clot   show
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what does it mean to agglutinate   show
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If you have Type A blood, what type of antibodies do you have   show
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show type B blood has anti-A antibodies  
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show type o blood has both anti-A and anti-B antibodies  
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if you have type AB blood, what type of antibodies do you have   show
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show Rh positive blood have no Rh antibodies  
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what type of antibodies does Rh negative blood have   show
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show white bloods cells have nuclei and other organells  
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show white blood cells help defend against invaders  
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show lymphatic system and connective tissue proper  
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show diapedesis is the ability that a WBC has to pass through the intact walls of the capillaries  
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what are 3 major functions of white blood cells   show
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show a greater than average/normal number of blood cells in the body  
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show margination is the WBC's ability to contact and adhere to a vessel wall  
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what can cause a WBC to migrate out of a blood stream   show
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show diapedesis is another term for emigration  
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show a gliding motion that is similar to the movement of an ameobiod  
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show the attractions that white blood cells have to specific chemical stimuli  
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show white blood cells have positive chemotaxis properties  
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show positive chemotaxis attracts inactive WBCs to pathogens, damaged tissue, and other active WBCs  
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name the two groups of white blood cells   show
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what are the three types of granulocytes   show
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show under a microscope, granulocytes have many granulations in the the cytoplasm  
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what group of white blood cells have lobed nuclei   show
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which white blood cell contains granulocytes in its cytoplasm, has a nucleus with 4 to 5 lobes, and appears colorless under a microscope   show
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name all the types of agranulocytes in blood   show
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what group of white blood cells are classified by having little to no granules in its cytoplasm   show
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show neutrophils, eosinophils, basophils, and monocytes  
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which white blood cells are also called microphages   show
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macrophages are _____________________ that have moved out of the blood stream and are actively phagocytic   show
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show lymphocytes (B and T cells) are part of specifi  
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show lymphocytes  
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which white blood cell makes up 70% of the bodies WBC population   show
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show neutrophils are the first to arrive and attack  
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show neutrophils release prostaglandins and leukotrienes that help with capillary permeability ant contribute to inflammations  
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what chemical released by neutrophils helps attract phagocytes and coordinate immune response   show
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show 10 hours (30 minutes when engulfing pathogens)  
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show 12 - 24 bacteria  
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what is included in pus   show
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what is a three letter word for a substance that includes cellular debris, wastes, and dead WBC's   show
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show eosinophils have bilobed nucleus and attack object that are covered in antibodies  
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what is the primary mode of attack for eosinophils   show
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eosinophils are especially effective against what type of invaders   show
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show eosinophils are sensitive to circulating allergens  
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at an injury site, which white blood cell releases enzymes that reduce inflammation and helps control the spread of inflammation to adjacent tissues   show
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show basophil are the rarest white blood cells  
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____________________________ migrate to an injury site by crossing the capillary endothelium   show
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which white blood cell discharges granules containing histamine and heparin into interstitial fluids   show
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what is the function of histamine   show
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what is the function of heparin   show
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show basophils help with dilation of blood vessels and help prevent blood clotting  
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the chemicals released by basophils attract which other white blood cells   show
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what white blood cell spends a relatively short life in circulation then migrates to the peripheral tissue where it becomes a macrophage   show
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which white blood cell has the capability to engulf foreign objects that are larger than themselves   show
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activated monocytes release chemical that attract and stimulate what other cells   show
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show fibroblasts begin producing scar tissue and begin to wall of the injured area  
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show most lymphocytes are located in CONNECTIVE TISSUE and LYMPHATIC SYSTEM than in the blood stream  
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name the three types of lymphocytes   show
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what type of immunity are T Cells responsible for   show
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show the T lymphocytes are responsible for specific immunity  
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show T Cells control the activities of other Lymphocytes  
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