ABO
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| The most immunogenic of all the blood group antigens | show 🗑
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| show | Unknown
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| This ABO phenotype has been linked with stomach ulcers | show 🗑
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| show | O
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| This ABO phenotype has been linked with gastric cancer | show 🗑
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| most common ABO blood type in most populations | show 🗑
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| show | For type O = IgG; for A and B= IgM
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| Describe Antibody reactivity for ABO blood group antibodies | show 🗑
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| Describe Transfusion reaction involving ABO antibodies | show 🗑
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| Describe severity of cases of Hemolytic disease of the newborn involving ABO system | show 🗑
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| He discovered the first blood group system, ABO, and earned a Nobel Prize. | show 🗑
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| show | A1 red cells express about 5 times more A antigen than A2 red cells
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| How/why do ABO antibodies occur? | show 🗑
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| show | N-acetylgalactosamine
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| Immunodominant sugar for blood group B | show 🗑
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| show | expressed on a wide variety of human tissues and are present on most epithelial and endothelial cells.
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| In individuals who are "secretors", a soluble form of the ABO blood group antigens is found in saliva and in all bodily fluids except for this. | show 🗑
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| ABO antibodies are of major clinical significance for two reasons: | show 🗑
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| show | Group O mothers with A or B baby because anti-A and anti-B formed in group O individuals tend to be of the IgG type (can cross placenta), whereas the anti-A and anti-B found in the serum of group B and A moms, is IgM
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| show | H(FUT1)
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| In saliva and other bodily secretions, the enzyme that synthesizes the H antigen is encoded by the __locus (FUT2). | show 🗑
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| show | The ABO locus is located on chromosome 9 at 9q34.1-q34.2.
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