Make sure to remember your password. If you forget it there is no way for StudyStack
to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password.
For details read our
Terms of Service.
Typically causes an acute hemolytic transfusion reaction
Describe severity of cases of Hemolytic disease of the newborn involving ABO system
No or mild disease
He discovered the first blood group system, ABO, and earned a Nobel Prize.
Austrian scientist, Karl Landsteiner
Describe the differences between A1 and A2 RBC phenotypes
A1 red cells express about 5 times more A antigen than A2 red cells
How/why do ABO antibodies occur?
ABO antibody production is stimulated when the immune system encounters the "missing" ABO blood group antigens in foods or in micro-organisms.
Immunodominant sugar for blood group A
Immunodominant sugar for blood group B
Are ABO antigens expressed on other tissues?
expressed on a wide variety of human tissues and are present on most epithelial and endothelial cells.
In individuals who are "secretors", a soluble form of the ABO blood group antigens is found in saliva and in all bodily fluids except for this.
ABO antibodies are of major clinical significance for two reasons:
they are naturally occurring and are found universally, and, they are highly reactive.
ABO related Hemolytic disease of the newborn tends to occur almost exclusively in moms with this blood type? Why?
Group O mothers with A or B baby because anti-A and anti-B formed in group O individuals tend to be of the IgG type (can cross placenta), whereas the anti-A and anti-B found in the serum of group B and A moms, is IgM
For A/B antigen synthesis to occur, a precursor called the_____ antigen must be present
In saliva and other bodily secretions, the enzyme that synthesizes the H antigen is encoded by the __locus (FUT2).
The ABO locus is located on chromosome
The ABO locus is located on chromosome 9 at 9q34.1-q34.2.