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ASCP Coag Hematology
ASCP Study coagualtion & hematology
| Question | Answer |
|---|---|
| Chemicals that prevent blood from clotting are called what? | Anticoagulants |
| Platelet peripheral zone is responsible for | Adhesion |
| Platelet Solu-Gel zone is responsible for | Contraction |
| Platelet organelle zone is responsible for | Secretion |
| Bernard Soulier syndrome | Platelet disorder with giant platelets causes a deficiency of Glycoprotein 1b a receptor for Von W Factor |
| Count for platelets in hemocytometer | |
| The term used to indicate that a wound has stopped bleeding is? | Hemostasis |
| Chemicals released from a vein by injury are called? | Vascular Factors |
| Chemicals released by platelets to induce narrowing of the blood vessel are known as? | Platelet Factor |
| Chemicals in the plasma that stops blood clotting are called? | Plasma Factor |
| All the individual blood factors will cause? | Vasoconstriction |
| Vascular Factor is also called? | Von Wilebrand's Factor |
| The messenger for platelets to aggregate at an injury site is? | Vascular Factor |
| The test for Von Wilebrands factor is the | Bleeding Time |
| Bleeding time test determines a deficiency in which factor | Vascular or Von Wilebrands |
| What is the normal value for the Bleeding Time? | less than 7.5 minutes |
| What is the test that replaces the BT | PFA or PFT Platelet Function Assay/Test |
| What changes to platelets does Vascular Factor affect? | Platelets grow fingers & become sticky |
| A hemostatic plug is made up of what? | platelet aggregates |
| Normally platelets are not sticky & don't adhere to vessel walls. When sticky, where do they adhere (anatomical) | Tunica media and adventitia |
| The outer layer of a vein is the... | Tunica adventia |
| The middle layer of a vein is the... | Tunica media |
| The inner layer of a vein is the... | Tunica intima |
| Which coagulation test is for platelet function? | PT Prothrombin |
| In what tube is the PT test drawn? | Light blue |
| What is a normal range for the PT? | 10-12 seconds |
| What drugs are used to reduce clotting in patients with a disorder of platelets? | Coumadin or Warfarin |
| Does the PT test for Intrinsic or Extrinsic factors | Extrinsic |
| What is the INR | International Normalized Results |
| What is the normal INR result? | between 0.9 and 1.1 INR |
| The formula for INR is... | Patient Results divided by the International normal. |
| When drawing blood from a patient on anticoagulants what is of concern? | bruising or hematoma |
| What is the test for Plasma Factors? | PTT Partial Thromboplastin time |
| PTT test is used to monitor patients on which anticoagulant? | Heparin |
| What is the normal value for a PTT? | 28-34 seconds |
| 7.5 minutes or less is normal value for which test? | BT |
| 10 - 20 seconds is a normal range for which test? | PT |
| 28 - 24 seconds is a normal range for which test? | PTT |
| PT screens for abnormal blood coagulation triggered by exposure of plasma to what? | Negatively charged surface |
| Platelets are receptive to what protein? | Fibrinogen |
| Aggregated platelets will combine with what to secure the hemostatic plug? | Fibrin strands |
| The final steps in forming a clot is to activate a mechanism to contract? | Platelet actomyosin |
| Von Wilebrands factor is found in which 2 places? | Plasma and vessel wall |
Created by:
Ladybug9537
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