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ASCP Coag Hematology

ASCP Study coagualtion & hematology

Chemicals that prevent blood from clotting are called what? Anticoagulants
Platelet peripheral zone is responsible for Adhesion
Platelet Solu-Gel zone is responsible for Contraction
Platelet organelle zone is responsible for Secretion
Bernard Soulier syndrome Platelet disorder with giant platelets causes a deficiency of Glycoprotein 1b a receptor for Von W Factor
Count for platelets in hemocytometer
The term used to indicate that a wound has stopped bleeding is? Hemostasis
Chemicals released from a vein by injury are called? Vascular Factors
Chemicals released by platelets to induce narrowing of the blood vessel are known as? Platelet Factor
Chemicals in the plasma that stops blood clotting are called? Plasma Factor
All the individual blood factors will cause? Vasoconstriction
Vascular Factor is also called? Von Wilebrand's Factor
The messenger for platelets to aggregate at an injury site is? Vascular Factor
The test for Von Wilebrands factor is the Bleeding Time
Bleeding time test determines a deficiency in which factor Vascular or Von Wilebrands
What is the normal value for the Bleeding Time? less than 7.5 minutes
What is the test that replaces the BT PFA or PFT Platelet Function Assay/Test
What changes to platelets does Vascular Factor affect? Platelets grow fingers & become sticky
A hemostatic plug is made up of what? platelet aggregates
Normally platelets are not sticky & don't adhere to vessel walls. When sticky, where do they adhere (anatomical) Tunica media and adventitia
The outer layer of a vein is the... Tunica adventia
The middle layer of a vein is the... Tunica media
The inner layer of a vein is the... Tunica intima
Which coagulation test is for platelet function? PT Prothrombin
In what tube is the PT test drawn? Light blue
What is a normal range for the PT? 10-12 seconds
What drugs are used to reduce clotting in patients with a disorder of platelets? Coumadin or Warfarin
Does the PT test for Intrinsic or Extrinsic factors Extrinsic
What is the INR International Normalized Results
What is the normal INR result? between 0.9 and 1.1 INR
The formula for INR is... Patient Results divided by the International normal.
When drawing blood from a patient on anticoagulants what is of concern? bruising or hematoma
What is the test for Plasma Factors? PTT Partial Thromboplastin time
PTT test is used to monitor patients on which anticoagulant? Heparin
What is the normal value for a PTT? 28-34 seconds
7.5 minutes or less is normal value for which test? BT
10 - 20 seconds is a normal range for which test? PT
28 - 24 seconds is a normal range for which test? PTT
PT screens for abnormal blood coagulation triggered by exposure of plasma to what? Negatively charged surface
Platelets are receptive to what protein? Fibrinogen
Aggregated platelets will combine with what to secure the hemostatic plug? Fibrin strands
The final steps in forming a clot is to activate a mechanism to contract? Platelet actomyosin
Von Wilebrands factor is found in which 2 places? Plasma and vessel wall
Created by: Ladybug9537