WVSOM -- Beta Oxidation and other FA oxidations
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| Oleate | 18C DB 9
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| Linoleate | 18C DB 9,12
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| Linolenate | 18C DB 9,12,15
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| Arachinoale | 20C DB 5,8,11,14
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| Which cells never use B Oxidation | RBCs and Brain Cells
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| Where does B oxidation occur | Mitochondria
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| B oxidation utilizes which kind of metabolism | aerobic
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| Uncommon Fatty Acids | Long chains with odd numbers of carbons
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| Common Fatty Acids | Long Chain (even numbers) and mono- or polyunsaturated FA
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| Medium Fatty Acid chains | 6-12 C
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| Short Fatty Acid Chains | 4 carbons
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| Very Long Acid Chains | more than 20 carbons
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| Triacylglycerol Lipolysis | Tracylglycerol -> Diacylglycerol -> Monoacylglycerol -> Glycerol
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| Long chain fatty acid cross the plasma membrane via | facilitated transport and diffusion
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| Fatty acids transported on what protein in plasma | albumin
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| How is ATP expended in the cytosol during B Oxidation | Fatty acids bound to acyl CoA molecules
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| Carnitine | transports Fatty Acyl into mitochondria
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| What binds to FA as soon as it enters the mitochondria | binds to another CoA
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| When does B Oxidation occur | in a fast
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| What mitochondria do not perform B oxidation | mitochondria in brain cells
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| major regulation of B oxidation | Adipose (hormone sensitive) Lipase
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| B oxidation Starting materials | Long Chain FA
NAD+
FAD
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| B oxidation products | Acetyl CoA
NADH
FADH2
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| How far are fatty acids cleaved during B oxidation | until there are only Acetyl CoA Molecules
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| How many FADH2 and NADH produced in B oxidation | 1 per each B oxidation
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| Propionyl- CoA | 3 carbons
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| When is propionyl CoA Produced | when Fatty acid chains have odd numbers
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| Where does Propionyl CoA enter the Kreb Cycle | production of Succinyl CoA
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| FADH2 production from B oxidation of unsaturated fatty acids | 1 less FADH2 per double bond
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| When are medium chain fatty acids B-oxidized | as soon as they are absorbed from the gut
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| w-oxidation produces | dicarboxylic acids
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| Where does w-oxidation occur | opposite end of fatty acid chain that B oxidation occurs
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| Peroxisomal Oxidation | oxidizes long, branched chains into fatty acyl-CoA that is then B oxidized
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| Peroxisomal and W-fatty acid oxidation regulation | only by the supply of fatty acids they oxidize
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Created by:
tjamrose
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