Muscle tissue, muscular system
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Types of muscle tissue | skeletal, cardiac, smooth
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Muscular system | includes only skeletal muscles
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Function of skeletal muscles | produce skeletal movement, maintain body position, support soft tissues, guard openings, maintain body temperature, store nutrient reserves
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Structures in skeletal muscle | muscle fibers, connective tissues, nerves, blood vessels
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Three layers of connective tissue within muscles | epimysium, perimysium, endomysium
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Epimysium | an exterior collagen layer connected to deep fascia; separates muscle from surrounding tissues
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Perimysium | connective tissue that surrounds fascicles; contains blood vessel and nerve supply to fascicles
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Fascicle | a bundle of muscle fibers
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Endomysium | connective tissue that surrounds individual muscle fibers, and contains capillaries and nerve fibers contacting muscle cells; also contains myosatellite cells that repair damage
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Myosatellite cell | a muscle stem cell
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Muscle attachment | connective tissue at the end of muscles made of the combined epimysium, perimysium, and endomysium that forms a connective tissue attachment to the bone matrix, either as a tendon or an aponeurosis
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Tendon | bundle of connective tissue that attaches muscle to bone matrix
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Aponeurosis | sheet of connective tissue that attaches muscle to bone matrix
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Function of nerves in the muscular system | connect muscles to the central nervous system, allowing voluntary control
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Nomenclature of skeletal muscles | a descriptive name followed by a location name
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Function of blood vessels in the muscular system | form an extensive vascular network that supplies nutrients and large amounts of oxygen, and carries away waste products
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Properties of skeletal muscle fibers | are very long; develop through fusion of myoblasts; contain hundreds of nuclei
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Myoblast | mesodermal stem cell that forms skeletal muscle cells
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Sarcolemma | cell membrane of a muscle fiber; maintains transmembrane potential to allow contractions
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Sarcoplasm | cytoplasm of a muscle fiber
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T tubule | transverse tubule; transmits action potential through the muscle fiber; allows entire fiber to contract simultaneously, and has same properties as the sarcolemma
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Myofibril | lengthwise subdivision within muscle fiber made up of myofilaments
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Myofilament | a protein filament responsible for muscle contractions
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Types of myofilaments | thin filaments made up of actin; thick filaments made up of myosin
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Sarcoplasmic reticulum | membranous structure surounding each myofibril that helps transmit action potential and forms terminal cisternae attached to the T tubule; similar structure to smooth endoplasmic reticulum
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Terminal cisterna | concentrates calcium ions via ion pumps, and releases them into sarcomeres to begin muscle contraction
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Triad | internal structure of a muscle fiber formed by one T tubule and two terminal cisternae
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Sarcomere | contractile unit of muscle that forms the structural unit of a myofibril, and forms visible patterns within the myofibril
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Muscle striations | a pattern of light (I band) and dark (A band) filaments within myofibrils
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A band | a dark, thick filament within the myofibril
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I band | a light, thin filament within the myofibril
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M line | the center of the A band, at the midline of the sarcomere
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Z line | the center of the I band, at the ends of the sarcomere
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Zone of overlap | the darkest area visible in the myofibril, where the A and I bands overlap
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H band | area around the M line that has thick filaments but no thin filaments
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Titin | a strand of protein that reaches from the tips of the thick filaments to the Z line, stabilizing the filaments
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Function of sarcomeres | contracts when calcium ions released by the sarcoplasmic reticulum cause the thin and thick filaments to interact
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Four proteins of thin filaments | F-actin, nebulin, tropomyosin, troponin
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Mnemonic for remembering thick and thin filaments | the "tin" in actin corresponds to the thIn filaments, which look lIght and form the I band; the A band looks dArk
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Types of fascicle organization | parallel, convergent, pennate
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Types of attachment sites for convergent muscles | tendon, aponeurosis, raphe
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Types of pennate muscles | unipennate (extensor digitorum), bipennate (rectus femoris), multipennate (deltoid)
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Sphincter | circular muscles that open and close to guard entrances of the body
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Orbicularis oris | the muscle that closes and opens the mouth
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Orbicularis oculis | the muscle that closes and opens the eye
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Lever | rigid, moving structure
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Fulcrum | fixed point
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Three functions of levers | changes direction of applied force, distance and speed of movement, effective strength of applied force
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First-class lever | fulcrum is in the center between the applied force and the resistance; for example, nodding yes
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Second-class lever | centers resistance between fulcrum and applied force, to move a large weight with a small force; for example, tiptoeing
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Third-class lever | centers applied force between resistance and fulcrum, to maximize speed and distance traveled; for example, flexion of the elbow
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Types of muscle functions | agonist, antagonist, synergist, fixator
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Agonist muscle | produces a particular movement
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Antagonist muscle | opposes movement of a particular agonist
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Synergist muscle | smaller muscle that assists a larger agonist
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Fixator muscle | stabilizes point of attachment of an agonist muscle
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Only two muscles without the word "muscle" in their correct names | platysma, diaphragm
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Platysma | flat muscle of the lower jaw
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Diaphragm | umbrella-shaped muscle that separates the thoracic and abdominal cavities
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Ways muscles are named | location in the body, origin and insertion, fascicle organization, relative position, structural characteristics, action
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Muscles of the eye | six extrinsic muscles (sclera), two intrinsic
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Six extrinsic muscles of the eye | superior rectus, medius rectus, inferior rectus, lateral rectus, superior oblique, inferior oblique
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Intrinsic muscles of the eye | ciliary, iris
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Ciliary muscle of the eye | controls the shape of the lens to focus vision
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Iris muscle | controls the size of the pupils
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Divisions of the muscular system | axial (60% of muscles), appendicular (40%)
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Six muscle groups of the head and neck | facial expression, extrinsic eye muscles, mastication, muscles of the tongue, muscles of the pharynx, anterior muscles of the neck
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Process of initiating contraction | Ca2+ ion binds to receptor on troponin molecule; troponin-tropomyosin complex changes, expressing the active site of F-actin
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Sliding filament theory | thin filaments slide along thick filaments toward the M line at the center of the sarcomere; width of the A zone stays the same, Z lines move closer together
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Five steps of the contraction cycle | exposure of active sites; formation of cross-bridges; pivoting of myosin heads; detachment of cross-bridges; reactivation of myosin
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Process of relaxation | Ca2+ concentrations fall; Ca2+ ions detach from troponin; active sites are re-covered by tropomyosin; tension gradually falls to resting levels; titin proteins recoil after stretching
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Neuromuscular junction | location of neural stimulation; action potential causes release of neurotransmitters into the synaptic cleft
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Action potential | electrical signal that travels along the nerve axon and ends at synaptic terminal
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Synaptic terminal | part of the neuron that releases acetylcholine into the synaptic cleft
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Acetylcholine | neurotransmitter that transmits action potential from a motor neuron to a muscle fiber by binding to membrane receptors on the sarcolemma, making it more permeable to sodium ions
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Synaptic cleft | gap between the synaptic terminal and motor end plate, where acetylcholine is released by the neuron and attaches to the motor end plate
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Motor end plate | portion of the sarcolemma that receives acetylcholine
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Cardiac muscle tissue | striated muscle tissue found only in the heart, notable for containing intercalated discs
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Intercalated discs | specialized contact points between cardiocytes made up of gap junctions and desmosomes that enhance molecular and electrical connections and conduct action potentials
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Smooth muscle tissue | nonstriated tissue with different functional characteristics from skeletal muscle; causes involuntary movement in the body, mainly in the cardiovascular (regulating blood pressure and flow), digestive (peristalsis, sphincters), and integumentary systems
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Muscles of the shoulders and upper limbs | position the pectoral girdle, flex and extend the shoulder and elbow, abduct and adduct the shoulder, and rotate the shoulder
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Muscles that position the pectoral girdle | trapezius, rhomboid, levator scapulae, serratus anterior, subclavius, pectoralis minor
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Muscles that abduct the shoulder | deltoid (agonist), supraspinatus (synergist)
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Muscle that adducts the shoulder | coracobrachialis
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Muscles that rotate the shoulder | subscapularis and teres major (medial), infraspinatus and teres minor (lateral)
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Muscle that extends the shoulder | latissimus dorsi
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Muscle that flexes the shoulder | pectoralis major
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Muscles of the rotator cuff | supraspinatus, subscapularis, infraspinatus, teres minor
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Muscles that flex the elbow | biceps brachii (agonist), brachialis and brachioradialis (synergists), triceps and anconeus (antagonists)
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Muscles that extend the elbow | triceps brachii (agonist), anconeus (synergist), biceps and brachioradialis (antagonists)
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Muscles that move the thigh | gluteal, lateral rotators, adductors, iliopsoas
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Gluteal muscles | gluteus maximus, gluteus medius and minimus, tensor fasciae latae
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Lateral rotators of the thigh | piriformis, obturator
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Adductors of the thigh | adductor magnus, adductor brevis, and adductor longus; pectineus, gracilis
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Hip flexors | psoas major, iliacus
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Extensors of the knee | four muscles of the quadriceps femoris
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Quadriceps femoris | vastus medialis, vastus intermedius, and vastus lateralis; rectus femoris
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Flexors of the knee | hamstring
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Hamstring muscles | biceps femoris, semitendinosus, semimembranosus
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