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Chapter 13 definitions

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Term
Definition
Plasma   Clear, extracellular matrix of blood; roles in clotting, the immune system, & regulation of fluid volume; 55% of bood  
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Formed elements   Cell and cell fragments that make up 45% of blood; consists of erythrocytes, leukocytes, & platelets  
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Hematocrit   Percentage of cells in a sample of blood; how much oxygen the blood can carry  
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Viscosity   Determined by the combination of plasma and blood cells; refers to how thick or sticky a fluid is  
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Hemopoiesis   Production of blood  
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Hemoglobin   Red pigment that gives blood its color; fills over 1/3 of the interior of an RBC  
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Globins   Ribbon-like protein chains in hemoglobin  
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Heme   Iron-containing molecule bound to each globin; each can combine with 1 molecule of oxygen  
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Erythropoiesis   Producing new erythrocytes; process takes 3-5 days  
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Erythropoietin   EPO; hormone secreted by the kidneys that stimulates red bone marrow to begin creating new erythrocytes  
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Reticulocyte   Immature form of an erythrocyte; takes 1-2 days to mature  
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Hemolysis   Excessive destruction of RBCs  
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Polycythemia   Excess of RBCs  
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Anemia   Deficiency of RBCs or hemoglobin  
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Hemolytic anemia   Results when too many RBCs are being destroyed  
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Pernicious anemia   Results from a lack of vitamin B12  
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Leukocytes   WBCs; fewest of the formed elements; 5 types in the body; all contain a neucleus; spend most of their lives in connective tissue  
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Granulocytes   WBCs containing a single multilobular nucleus; 3 types include neutrophils, eosinophils, and basophils  
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Agranulocytes   WBCs lacking cytoplasmic granules and the neuclei lack lobes; 2 types include lymphocytes and monocytes  
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Leukopenia   Abnormally low WBC count  
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Leukocytosis   Elevated WBC count  
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Platelets   Thrombocytes; 2nd most abundant formed element; key role in hemostasis; live about 7 days  
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Hemostasis   Stopping bleeding  
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Reaction cascade   Series of reactions in which each depends on the product of the preceding reaction  
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Heparin   Anticoagulant secreted by basophils and mast cells  
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Thrombus   Unwanted blood clot inside a vessel  
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Embolus   Piece of clot breaks off and circulates through the blood stream  
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Antigen   Agglutinogen; protein carried on the surface of each red blood cell; 2 types are A & B  
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Antibodies   Agglutinins; carried by plasma; against the antigens of other blood types  
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Agglutination   Large clumps of antigen-antibody molecules  
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