Chapter 13 definitions
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Plasma | Clear, extracellular matrix of blood; roles in clotting, the immune system, & regulation of fluid volume; 55% of bood
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Formed elements | Cell and cell fragments that make up 45% of blood; consists of erythrocytes, leukocytes, & platelets
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Hematocrit | Percentage of cells in a sample of blood; how much oxygen the blood can carry
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Viscosity | Determined by the combination of plasma and blood cells; refers to how thick or sticky a fluid is
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Hemopoiesis | Production of blood
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Hemoglobin | Red pigment that gives blood its color; fills over 1/3 of the interior of an RBC
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Globins | Ribbon-like protein chains in hemoglobin
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Heme | Iron-containing molecule bound to each globin; each can combine with 1 molecule of oxygen
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Erythropoiesis | Producing new erythrocytes; process takes 3-5 days
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Erythropoietin | EPO; hormone secreted by the kidneys that stimulates red bone marrow to begin creating new erythrocytes
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Reticulocyte | Immature form of an erythrocyte; takes 1-2 days to mature
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Hemolysis | Excessive destruction of RBCs
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Polycythemia | Excess of RBCs
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Anemia | Deficiency of RBCs or hemoglobin
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Hemolytic anemia | Results when too many RBCs are being destroyed
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Pernicious anemia | Results from a lack of vitamin B12
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Leukocytes | WBCs; fewest of the formed elements; 5 types in the body; all contain a neucleus; spend most of their lives in connective tissue
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Granulocytes | WBCs containing a single multilobular nucleus; 3 types include neutrophils, eosinophils, and basophils
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Agranulocytes | WBCs lacking cytoplasmic granules and the neuclei lack lobes; 2 types include lymphocytes and monocytes
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Leukopenia | Abnormally low WBC count
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Leukocytosis | Elevated WBC count
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Platelets | Thrombocytes; 2nd most abundant formed element; key role in hemostasis; live about 7 days
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Hemostasis | Stopping bleeding
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Reaction cascade | Series of reactions in which each depends on the product of the preceding reaction
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Heparin | Anticoagulant secreted by basophils and mast cells
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Thrombus | Unwanted blood clot inside a vessel
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Embolus | Piece of clot breaks off and circulates through the blood stream
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Antigen | Agglutinogen; protein carried on the surface of each red blood cell; 2 types are A & B
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Antibodies | Agglutinins; carried by plasma; against the antigens of other blood types
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Agglutination | Large clumps of antigen-antibody molecules
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