Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Apoptosis Dr. F

Apoptosis

QuestionAnswer
If you have mutated Ced 3 or Ced 4 will the cells die? No. They inactivate cell death
If you knocked out Ced 9 will cells die? Yes. Ced 9 is a repressor of death
What Ced is Bcl-2 homologous to? Ced 9
When caspase 3 effector cleaves ICAD what does it activate? CAD
Name intiator caspases Casp 8, Casp 9 and Casp 10
In order for an effector caspase to be activated what must happen? It must be cleaved
In order for an initiator capase to be activated what must happen? It must be dimerized and cleaved. Once you bring the monomers together as a dimer it autocleaves
Name the caspases apart of the extrinsic pathway Casp 8 and casp 10
Name the caspases apart of the intrisic pathway Casp 9
Describe the extrinsic pathway TNF binds to the ligand and then attracts adaptor protein and binding through adaptor proteins activates the initiator caspase by forced dimerization
What happens after intiator caspases are activated? They activate effector caspases leading to a caspase cascade.
Describe the intristic pathway Ced 4/Apaf 1 form a complex with a specific initiator procaspase causing its activation. Then cleaves and activates the effector caspase.
Do increased levels of Bcl-2 induce or repress apoptosis? repress
Do increased levels of Bax/Bak induce or repress apoptosis? Induce
What is Ced-3 hoomologous to in mammals? ICE (interleukin 1B converting enzyme)
Popular Histology sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards