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Disease Final
Mycobacterium, Chlamydia, Neisseria
| Question | Answer |
|---|---|
| Mycobacterium is what staining? | acid fast |
| Obligate aerobes, poor gram staining, acid fast stain due to waxy/hydrophobic lipid layer | mycobacterium |
| Two forms of staining for Mycobacterium (TB) | Acid fast, Ziehl Neelson Stain |
| 2 factors for Mycobacterium | Resp spread; virulence is cell envelope |
| granuloma, central caseating necrosis, Langhan giant cells, mononuclear cells, malignant infiltrates, most likely dx? | TB via Mycobacterium tuberculosis |
| Specialized culture media of Mycobacteria | Lowenstein-Jensen rapid broth provides high lipid content |
| Granuloma, acid fast, Ziehl-Neelson=acid fast bacilli means | Mycobacterium |
| Opportunistic Mycobacteria in immunocompromised | MAI, Myco. avium-intracellullare |
| Acid fact organism causing leprosy | Myco. leprae |
| ipsilateral lymphadenopathy due to infected lymph drained along interstitium to hilar and mediastinal lymph; characteristic of primary TB along with hilar lymph node | Ghon Comples |
| what is the most likely cause of infection by an acid-fast organism in a 27 y/o with AIDS | Mycobacterium avium |
| destroys peripheral/motor nerves; untreated casn lead to painful renal inflammation, anaesthetize extremities, deformity/incurable blindness; physical injury/impaired circulation | leprosy |
| Obligate intracellular that cannot make ATP, like a virus; but has borth DNA/RNA like bacteria | Chlamydia |
| Invades columnar epithelium, where inflammation leads to destructiong: Cevicitis, Nongonococcal urethritis, inclusion conjuctivitis, infant PNA; most common STD in the US | Chlamydia trachomatis |
| acquired during delivery, infection 4-11 weeks after birth, resp distress, rhinitis, cough, afebrile | Chlamydia trachomatis |
| disease called granular conjunctivis is contagious, chronic inflamm of mucus membranes | Trachoma |
| chlamydia inicated by what type of labeling? | Direct Immunofixation antibody labeling (DIF) |
| disease in pet/zoo/flocks of birds, exposed to infected bird or dried excrements, atypical PNA, HA, fever, mac rash, nonproductive cough, rales | Chlamydia psittaci |
| spread by resp secretions, atypical PNA, bronchitis, sinusitis, not an STD; inclusions | chlamydia pneumoniae |
| Non-gram staining, smallest free bacteria than larger viruses, resp spread, attaches to epithelium leading to necrosis, atypical walking PNA, streaky lung infiltrates on CXR, dx based on presentation (not culture) | Mycoplasma pneumoniae |
| species of mycoplasma, metabolizes urea (urea-lytic), causes urethritis and prostatitis | Ureaplasma urealyticum |
| G(-), kidney bean shape diplococci and the only pathogenic G(-) cocci | Neisseria |
| phagocytic uptake is reduced due to what virulence factor | capsule |
| reservoir/transmission of neisseria? | nasopharynx; spread by Respiratory |
| < 1y/o, Army recuits in close quarters, or asplenic pt/functional asplenia are at risk for | neisseria meningitidis |
| meningococcemia with acute fever, rash, joint/muscle pain and petechial rash; also Waterhouse-Friderichsen syndrome | Neisseria meningitidis |
| Gram (-) septic shock, HoTN, Petechial leasions, adrenal hemorrhage, DIC are symptpoms of what Neisseria disease? | Waterhouse-Friderichsen Syndrome |
| type of media of Neisseria | blood, chocolare, Thayer Martin VCN |
| 4 Virulence factors for Neiserria gonorrhea | Pili to attach mucosal cells, changing antigens to prevent immunity to reinfection, IgA protease, Endotoxin |
| Urethritis, epididymitis, anorectal lesions, pharyngitis in who? | Male - gonorrhea |
| Asymptomatic endocervicitis, PID, anorectal lesions ,pharyngitis in who? | Female - gonorrhea |
| Neiserria causes infant infection that is the reason for prophylactic tx called? | ophthalmia neonatorium |
| G(-)diplococci, aerobic cultures on Thayer-Martin media reveal oxidase positive colonies | Neisseria gonorrhea |
| what does the specialized media do for Neisseria? | inhibits normal flora, eliminates G(+), not G-stains and are not cocci |
| CSF eval shows neutrophils, low glucose, high protein, G(-) diplococci. infection is likely to be | Neisseria meningitidis |
Created by:
emtdan85
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