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Antibiotics-target

Antibacterial agents

QuestionAnswer
Antibiotics, group I -Microorganisms, subgroup -Actinomyces (antifungal). Name classes of antibiotics. 1, Imidazoles 2, Different
Antibiotics, group II -Fungi. Side effects. Allergy, may lead to: anafylactic shock, skin rash, serum sickness, fever, nephritis.
Streptomycin -side effect. Could lead to permanent damage of the auditory nerve -> Hearing loss.
Tetracyclines -side effects. 1, Antibiosis -> Candidosis 2, Hepatic- and kidney damage 3, Brown discoloration of teeth (in children)
Chloramphenicol -side effects. Bone marrow suppression, leading to Aplastic anemia.
Name antibiotics that are very toxic to toxic. Very toxic: Vancomycin. Toxic products: 1, Nystatin (antifungal) 2, Antitumoral a/b (Actinomycin, Mitomycin, Dactinomycin) 3, Polymixin B, Gramicidin (antibacterial)
Generic name of: Penicillin -natural. 1, Penicillin G 2, Penicillin V
Generic name of: Penicillin -semisynthetic 1, Ampicillin 2, Methicillin 3, Carbenicillin 4, Oxacillin
Generic name of: Cephalosporins G1 1, Cephalotin 2, Cephazolin 3, Cephapirin
Generic name of: Cephalosporins G2 1, Cefamandole 2, Cefuroxime
Generic name of: Cephalosporins G3 and G4 1, Cefotaxime -G3 2, Ceftriaxone -G3 1, Cefpirome -G4
Generic name of: Aminoglycosides 1, Streptomycin 2, Kanamycin 3, Neomycin 4, Gentamycin
Generic name of: Tetracyclines 1, Oxytetracycline 2, Chlortetracycline 3, Tetracycline 4, Doxycycline 5, Minocycline
Generic name of: Macrolides 1, Erythromycin 2, Azithromycin 3, Clarithriomycin
Generic name of: Imidazoles 1, Clotrimazole 2, Miconazole 3, Ketoconazole
Generic name of: Different (actinomyces-antibacterial) 1, Lincomycin 2, Clindamycin 3, VANCOMYCIN 4, Rifamycin 5, Rifampin
Generic name of: Different (actinomyces-antifungal) 1, Nystatin 2, Amphotericin B
Generic name of: Different (actinomyces-antitumoral) 1, Actinomycin 2, Mitomycin 3, Dactinomycin
Generic name of: Different (Bacteria-antibacterial) 1, Polymixin B 2, Bacitracin 3, Gramicinin 4, Mupirocin 5, Colistins
Generic name of: Different (human/animal-antibacterial) 1, Lysozome 2, Erythrin 3, Spermine
Generic name of: Different (plant-antibacterial) 1, Phytoncides
Target and mechanism of action for: Penicillin -natural Narrow spectrum Gr+ Gr- Spirochetes Inhibit CW synthesis
Target and mechanism of action for: Penicillin -semisynthetic Broad spectrum Inhibit CW synthesis
Target and mechanism of action for: Cephalosporins G1 Good Gr+ Modest Gr- Inhibit CW synthesis
Target and mechanism of action for: Cephalosporins G2 Good Gr+ Better Gr- Inhibit CW synthesis
Target and mechanism of action for: Cephalosporins G3 Good Gr- Modest Gr+ Ps.aeruginosa Inhibit CW synthesis
Target and mechanism of action for: Cephalosporins G4 Good Gr- Ps.aeruginosa Inhibit CW synthesis
Target and mechanism of action for: Aminoglycosides Enteric Gr- Ps.aeruginosa Bactericidal effect, inhibit protein synthesis
Target and mechanism of action for: Tetracyclines Very broad spectrum Gr+ Gr- Rickettsias and Chlamydias Bacteriostatic effect
Target and mechanism of action for: Chloramphenicol Broad specturm Gr+ Gr- Rickettsias, Chlamydias and anaerobes Bacteriostatic effect, inhibit protein synthesis
Target and mechanism of action for: Macrolides Narrow spectrum Gr+ Gr- Legionella, C.diphteriae, Mycoplasmas, Chlamydias Bacteriostatic effect, inhibit protein synthesis
Target and mechanism of action for: VANCOMYCIN Very narrow spectrum against multiresistant bacteria. Bactericidal effect, inhibit CW synthesis
Target and mechanism of action for: Rifamycin and Riampin Narrow spectrum Gr+ (even multiresistant) M.tuberculosis Bactericidal effect, inhibit synthesis of mRNA
Target and mechanism of action for: Imidazoles Broad spectrum antifungals Candida, dermatophytes and systemic fungal infections. Interfere w/ sterole synthesis which inhibits cell membrane synthesis, plus anitmetabolic effects.
Target and mechanism of action for: Polymixin B Topical use in wound infections of Gr- Bactericidal effect, inhibit cell membrane synthesis.
Created by: gustafb82