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Gram + Rods, Anaerobic

Gram + Rods, Anaerobic Clostridium perfringens, Clostridium tetani, Clostridium difficile, Clostridium Botulinum
Clostridium perfringens: Labs Catalase -
Clostridium perfringens: Toxins Enterotoxins, Alpha toxin
Clostridium perfringens: Diseases Food poisoning, Gas gangrene, Endometritis, Cellulitis
Clostridium perfringens: Treatment Penicillin G, Metronidazole, Hyperbaric oxygen
Clostridium perfringens: Transmission Spores in soil, dust, and air, entering wound sites
Clostridium tetani: Labs Catalase -
Clostridium tetani: Toxins Spore-forming; toxin blocks inhibition--> lock jaw, opisthotonic posturing
Clostridium tetani: Diseases Lockjaw/opisthotonic
Clostridium tetani: Treatment Metronidazole, Tetanus anti-toxin, Respiratory support, Control of rigidity and spasms with benzodiazepines
Clostridium tetani: Transmission Spores occur in soil and disease occurs by entry of spores into wound sites; umbilical stump infection in neonates
Clostridium tetani: Vaccine DPT
Clostridium difficile: Labs Catalase -
Clostridium difficile: Toxins Flagella, spores with enterotoxins
Clostridium difficile: Diseases Pseudomembranous colitis, Bloody diarrhea
Clostridium difficile: Treatment IV Metronidazole, Oral Vancomycin, Water and electrolytes
Clostridium difficile: Transmission Spores infecting wound sites
Clostridium botulinum:Labs Catalase -
Clostridium botulinum:Toxins Blocks acetylcholine release
Clostridium botulinum:Diseases Diffuse paralysis
Clostridium botulinum: Treatment Botulinum anti-toxin, Metronidazole, Vanc
Clostridium botulinum:Transmission Airborne spores
Created by: vmed