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OCR Gene Therapy

Explanations and differances for somatic and germ line gene therapy by Ben S.NCS

QuestionAnswer
Gene therapy is the treatment of _______ ________ Genetic Disorders
Gene therapy involves the use of molecular _______ __________ techniques. Genetic Technology
Any cell forming the body of an organism (Body cells) are known as _______ Somatic
The sperm, egg, zygote and unspecialised cells of early embryos are known as ____ ____ cells Germ line
Somatic cell gene therapy involves Augmentation - where an absense of a gene product is solved by engineering a funtioning copy of a gene and inserting it into a specialised cell resulting in _______ _________ of the absent polypeptide Protein synthesis
The working allele copies are inserted into the gene by liposomes which are __________ ________ Artificial vesicles
Somatic treatment is short lived due to the specialised cells containing the gene not ________ and passing on the allele dividing
Getting the alleles into the genome is difficult. Gentically modified _______ may be used, as well as Liposomes, however these can prove inefficient and the body may become immune to the vector. viruses
The ethical reasons against somatic cell gene therapy is _______ as the manipulations are restricted to the parent and will not effect their children. limited
With Germ line treatment the allele is placed into the germline cells, it is long lived aa the functional allele is placed into ____ _____ stem cells
Germ line treatment is easier to perform, although there are ethical issues about ________ the human genome altering
Created by: Doney93
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