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Gram - Spirochetes

Gram - Spirochetes Borrelia burgdorferi, Treponema pallidum, Leptospirosis interrogans
Borrelia burgdorferi: Labs Lyme Serology- EIA and Western Blot
Borrelia burgdorferi: Toxins Lipid A/LOS, OspA--> OspC
Borrelia burgdorferi: Acute Disease Fever, Bull's eye rash, Myalgias and arthralgias, Meningeal irritation
Borrelia burgdorferi: Chronic Disease Meningoencphalitis, myocarditits, and disabling recurrent arthritis
Borrelia burgdorferi: Disease Lyme Disease
Borrelia burgdorferi: Treatment Oral doxycycline, ceftriaxone, amoxicillin, or erythromycin
Treponema pallidum: Labs Microaerophilic, Dark field immunoflourescent microscopy, RPR, VDRL
Treponema pallidum: Toxins Endotoxins, Hyaluronidase
Treponema pallidum: Primary disease Painless chancre that is contagious
Treponema pallidum: Secondary disease headache, Maculo-papular centripetal rashes, Arthralgias
Treponema pallidum: Latent disease Condyloma lata appear with recurrences
Treponema pallidum: Congenital disease Transplacental transmission
Treponema pallidum: Tertiary disease Neurosyphilis, Gummatous, and Cardiovascular disease
Treponema pallidum: Treatment Benzathine Penicillin, Pen G, Doxycycline
Leptospira interrogans: Labs Obligate aerobe
Leptospira interrogans: Toxins Endotoxins, Hyaluronidase
Leptospira interrogans: Acute disease Flu-like febrile illness with bacteremia
Leptospira interrogans: Recurrent disease Fever, Aseptic meningitis
Leptospira interrogans: Treatment Penicillin G, Doxycycline, Ceftriaxone
Leptospira interrogans: Transmission Zoonotic transmission
Created by: vmed