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Spirochetes
Gram - Spirochetes
Question | Answer |
---|---|
Gram - Spirochetes | Borrelia burgdorferi, Treponema pallidum, Leptospirosis interrogans |
Borrelia burgdorferi: Labs | Lyme Serology- EIA and Western Blot |
Borrelia burgdorferi: Toxins | Lipid A/LOS, OspA--> OspC |
Borrelia burgdorferi: Acute Disease | Fever, Bull's eye rash, Myalgias and arthralgias, Meningeal irritation |
Borrelia burgdorferi: Chronic Disease | Meningoencphalitis, myocarditits, and disabling recurrent arthritis |
Borrelia burgdorferi: Disease | Lyme Disease |
Borrelia burgdorferi: Treatment | Oral doxycycline, ceftriaxone, amoxicillin, or erythromycin |
Treponema pallidum: Labs | Microaerophilic, Dark field immunoflourescent microscopy, RPR, VDRL |
Treponema pallidum: Toxins | Endotoxins, Hyaluronidase |
Treponema pallidum: Primary disease | Painless chancre that is contagious |
Treponema pallidum: Secondary disease | headache, Maculo-papular centripetal rashes, Arthralgias |
Treponema pallidum: Latent disease | Condyloma lata appear with recurrences |
Treponema pallidum: Congenital disease | Transplacental transmission |
Treponema pallidum: Tertiary disease | Neurosyphilis, Gummatous, and Cardiovascular disease |
Treponema pallidum: Treatment | Benzathine Penicillin, Pen G, Doxycycline |
Leptospira interrogans: Labs | Obligate aerobe |
Leptospira interrogans: Toxins | Endotoxins, Hyaluronidase |
Leptospira interrogans: Acute disease | Flu-like febrile illness with bacteremia |
Leptospira interrogans: Recurrent disease | Fever, Aseptic meningitis |
Leptospira interrogans: Treatment | Penicillin G, Doxycycline, Ceftriaxone |
Leptospira interrogans: Transmission | Zoonotic transmission |