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MSUAZ Clin Lab Med 1
CBC, CMP, UA, Na, K
| Question | Answer |
|---|---|
| Bacterial Infection: What blood results are seen? | Leukocytosis (elevated WBCs), Neutrophilia (elevated neutrophils) |
| Inflammation: What blood results are seen? | Leukocytosis (elevated WBCs), Neutrophilia (elevated neutrophils) |
| Glucocorticosteroid Use: What blood results are seen? | Leukocytosis (elevated WBCs) |
| Viral Infection: What blood results are seen? | Monocytosis (elevated monocytes)* Leukopenia (decreased WBCs), Neutropenia (decreased neutrophils), Lymphocytosis (elevated lymphocytes), |
| Overwhelming bacterial infection: what blood results are seen? | Leukopenia (decreased WBCs), Neutropenia (decreased neutrophils) |
| Bone marrow failure: what blood results are seen? | Leukopenia (decreased WBCs) |
| Autoimmune disease: what blood results are seen? | Leukopenia (decreased WBCs) |
| Leukemia: what blood results are seen? | Neutrophilia (increased neutrophils), Basophilia (increased basophils) if CML, Lymphocytosis (increased lymphocytes) if lymphocytic leukemia, Lymphocytopenia (decreased lymphocytes), Thrombocytopenia (decreased platelets) |
| Aplastic anemia: what blood results are seen? | Neutropenia (decreased neutrophils) |
| Myeloproliferative diseases (CML): What blood results are seen? | Basophilia (increased basophils) |
| Acute allergic reactions: what blood results are seen? | Basopenia (decreased basophils) |
| Hyperthyroidism: what blood results are seen? | Basopenia (decreased basophils |
| Neoplasm: what blood results are seen? | Leukocytosis (increased WBCs), Eosinophilia (increased eosinophils) |
| Allergic Reactions: what blood results are seen? | Basopenia (decreased basophils) if acute, Eosinophilia (increased eosinophils) |
| Addison's Disease: what blood results are seen? | Eosinophilia (increased eosinophils) |
| Collagen Vascular Disease (Lupus): what blood results are seen? | Eosiniphilia (increased eosinophils) |
| Coccidiomycosis: what blood results are seen? | Eosinophilia (increased eosinophils) |
| Parasites: what blood results are seen? | Eosinophilia (increased eosinophils), Monocytosis (increased monocytes) like Malaria |
| Corticosteroid Use: what blood results are seen? | **Lymphocytopenia (decreased lymphocytes), eosinopenia (decreased eosinophils), Monocytopenia (decreased monocytes) |
| Mononucleosis or Viral Hepatitis: what blood results are seen? | Lymphocytosis (increased lymphocytes) |
| Chronic Inflammatory Disorders (ulcerative colitis, collagen vascular disorder- lupus): what blood results are seen? | Monocytosis (increased monocytes) |
| Malaria Parasitic Infection: what blood results are seen? | Monocytosis (increased monocytes) |
| Polycythemia Vera: what blood results are seen? | Thrombocytosis (increased platelets) |
| Postsplenectomy: what blood results are seen? | Thrombocytosis (increased platelets) |
| Estrogens and Oral Contraceptives: what blood results are seen? | Thrombocytosis (increased platelets) |
| Idiopathic Thrombocytopenic Purpura: what blood results are seen? | Thrombocytopenia (decreased platelets) |
| Thrombotic Thrombocytopenic Purpura: what blood results are seen? | Thrombocytopenia (decreased platelets) |
| Cirrhosis: what blood results are seen? | Thrombocytopenia (decreased platelets) |
| Anemia: what blood results are seen? | Thrombocytopenia (decreased platelets) |
| What is the most common form of granulocyte? | Neutrophil |
| Immature neutrophils are called what? | Bands |
| Which two granulocytes are involved in allergic reactions? | Basophils and Eosinophils |
| Which class of WBC have granules in their cytoplasm and multilobed nuclei? | Granulocytes |
| Which granulocyte phagocytoses bacteria? | Neutrophils |
| Which WBC type fights acute viral infections and chronic bacterial infections? | Lymphocytes |
| Leukocytosis with a left shift due to increased neutrophils and bands indicates what condition? | Acute bacterial infection |
| Decreased hemoglobin, hematocrit, microcytic MCV, hypochromic MCHC, and elevated RDW indicate what condition? | Iron deficient anemia |
| 5 Common causes of iron deficient anemia? | Menstrual blood loss, pregnancy, GI blood loss, decreased iron absorption, lactation |
| Causes of reduced RBC production that results in anemia? | B12, folate, iron deficiency, bone marrow failure, renal failure (decreased erythropoietin) |
| Causes of increased RBC destruction that results in anemia? | Hemolysis |
| 3 types of microcytic (decreased MCV) anemia? | Iron deficiency, Lead poisoning (basophilic stippling), Thalassemia (hereditary disorder with reduced synthesis of globin chains) |
| 2 types of macrocytic anemia? | Vitamin B12 deficiency, and Folate deficiency |
| 3 types of normochromic anemia? | Anemia of chronic disease, renal failure (decreased erythropoietin), and acute blood loss |
| A peripheral blood smear shows microcytic RBCs out of proportion to the degree of anemia, poikilocytosis, target cells, and nucleated RBCs. What condition might these results indicate? | Thalassemia |
| Increased hemoglobin and hematocrit levels indicate what 4 possible conditions/situations? | Dehydration, Polycythemia vera, Smoking/COPD, and High Altitude |
| A patient presents with HA, dizziness, tinnitus, blurred vision, fatigue, pruritis after a warm shower/bath, engorged retinal veins, thrombosis, splenomegaly, ^hemoglobin, ^hematocrit, leukocytosis, thrombocytopenia, & ^RBC mass. What do they have? | Polycythemia vera |
| Thrombocytosis (increased platelet levels), is commonly indicative of what condition? | Malignancy |
| What are the two types of thrombocytopenia? | Idiopathic thrombocytopenic purpura, and Thrombotic Thrombocytopenic purpura (rare) |
| In what 2 populations is idiopathic thrombocytopenic purpura common in? | Children, AIDS patients |
| What is the treatment for polycythemia vera? | Phlebotomy |
| A patient presents with petechiae, purpura, epistaxis, menorrhagia, and thrombocytopenia likely has what condition? | Idiopathic Thrombocytopenic Purpura |
| What is the treatment for idiopathic thrombocytopenic purpura? | Self-limited in kids, corticosteroids in adults or splenectomy if unresponsive |
| CBC results of decreased hemoglobin, decreased hematocrit, variable MCV, hypochromic MCHC, with peripheral smear of ringed sideroblasts, poikilocytosis, and anisocytosis indicates what condition? | Sideroblastic Anemia |
| CBC results of decreased hemoglobin, decreased hematocrit, normocytic MCV, and normochromic MCHC indicate what 3 conditions? | Anemia of Chronic Disease, Hypothyroidism, or liver disease |