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LECT_2

Potassium disorders

QuestionAnswer
hypoKalemia - primary hyperaldosteronism (2) Conn's syndrome, bilateral adrenal hyperplasia
hypokalemia - primary hyperreninism (3) renin secreting tumor, renovascular HTN, accelerated HTN
hypokalemia - NON-Aldo MC excess (2) Cushing's, high cortisol
HypoK and HTN (1) Liddle syndrome
hypokalemia INCREASED Distal Na Delivery (5) Diuretics, Osmotic diuresis, Bartter's, Gitelman's, Mg deficiency
hypokalemia - NON- reabsorbable IONS (5) Penicillins Ketoacidosis, metabolic alk. (vomit), prox. RTA, acetazolamide
Cellular redistribution causes of hypoKalemia (2) Alkalosis, HypoPP
hypokalemia with <20 renal excretion GI loss, probably
hypokalemia with >20mEq/L and low EABV serum [HCO3]
hypokalemia with >20mEq/L and high EABV check renin/aldo levels
hypokalemia with >20mEq/L and high EABV - ^R, ^A renal artery stenosis
hypokalemia with >20mEq/L and high EABV - vR, ^A Adrenal adenoma
hypokalemia with >20mEq/L and high EABV - vR, vA Cushing's, Liddle
hypokalemia with >20mEq/L and high EABV > low [HCO3] RTA
hypokalemia with >20mEq/L and high EABV > high [HCO3] check Urine [Cl]
hypokalemia with >20mEq/L and high EABV > high [HCO3] > high urine [Cl] (4) diuretics, Mg def., Bartter's, Gitelman
hypokalemia with >20mEq/L and high EABV > high [HCO3] > low urine [Cl] NRA
Primary decr in Distal Na delivery (2) acute oliguric renal failure, chronic renal failure
Primary DECR in MC activity (4) Addison's, hyporeninemic hypoaldosteroism, ACEi, adrenal biosynthetic defects
Distal tubular defects (2) intrinsic renal disease, diuretics (amiloride, spironolactone, triamterene)
Cellular redistribution (6) cell death/ischemia, acidosis, hyperosmolality, succinylcholine, hyperPP, insulin def.
HypoK; neuromuscular (2) weakness & flaccid paralysis, Rhabdomyolysis
HypoK; CV cardiac arrhythmias
hypoK; Renal (2) conc. defect, metabolic alkalosis
hypoK; metabolic glucose intolerance
hyperK; CV cardiac arrest; level of danger is predicted by EKG
hyperK: neuromuscular paresthesias¶lysis
bactrim effect on K excretion? blocks it! - K retention
hippurate, penicillins, salicylates, toluene (glue sniffing) all NON-absorbable anions - K -wasting
hyperK Rx: CaCl, beta-blockers, kayexalate, insulin
hypoK Rx correct the underlying cause **treat hypoK, BEFORE treating MAc
Created by: MATTADOR
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