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Biochem Exam
| Question | Answer |
|---|---|
| NAD Vitamin | Niacin (B3) |
| FAD Vitamin | Riboflavin (B2) |
| TPP Vitamin | Thiamine (B1) |
| CoA vitamin | Pantothenate (B5) |
| Folic Acid | Tetrahydrofolate |
| Pyroxidal Phosphate | Pyridoxine (B6) |
| Vmax | max velocity of a rxn |
| Km | concentration of substrate |
| Kd | measure of binding |
| Competitive Inhibitor | binds substrate binding site, decrease rxn rate, increased km |
| Non-Competitive Inhibitors | binds allosteric substrate, |
| GLUT 1 | highly expressed in erythrocytes and high affinity for glucose |
| GLUT 2 | low affinity transporter, liver |
| GLUT 3 | high affinity transporter, brain |
| GLUT 4 | insulin sensitive, adipose and muscle |
| VIII | stimulates platelet degredation, activates 10, activated by thrombin |
| X | stimulates prothrombin to thrombin |
| III | Tissue factor, activates 7 |
| VII | beginas cascade based on trauma |
| XIII | crosslinks (hard clot formation) |
| V | activated by thrombin, cofactor to 10 to change prothrombin to thrombin |
| Fibrinogen | with thrombin (2a) causes fibrin to form soft clot |
| Thrombin | activates 11 |
| coagulation cofactors | 8 and 5 |
| Externsic Pathway | 3-7-10 |
| Intrinsic | 12-11-9 (with 8)-10 |
| aPTT | intrinsic and common pathway |
| PTT | extrensic and common pathway |
| Hemophilia A | deficiet factor 8 |
| Hemophilia B | deficit factor 9 |
| Heparin | blocks coagulation by inhibiting factor 2 (AKA Thrombin) |
| Inhibitors of Coagulation | Protein S, C, Serpins, Heparin |
| type I collagen | main type CT, bone, teeth, encapsulated organs resist force, tension and stretch |
| type II collagen | cartilage resists intermittent pressure |
| Type III Collagen | found in reticular fibers scaffolding for specialized cells |
| Type IV Collagen | basement membrane suppoer and filtration |
| Type VII Collagen | skin, eye, etc connects basement membrane to ECM |
| Mast Cells | allergies-secrete histamine and heparin |
| Plasma Cells | produce antiboides, made in marrow |
| Anaphylaxis | hypersensitivity to histamine, drop in BP and close airways |
| histamine | increases contratcion of vessels, permeability of vessels and mucous production |
| MMP (metalloprotesases) | breaksdown damaged fibers via phagocytosis |
| apocrine sweat glands | 3 A's:axilary, anal, aerolar ducts secrete via exocytosis |
| eccrine sweat glands | watery secretion and ducts |
| sebaceous glands | oily substance to hair follicles whole cells into gland |
| Pilosebaceous unit | hair shaft, sebaceous gland, arrector pili muscle, hair follicle and hair root |
| Basal Cell Carcinoma | arises from follicular bulge of hair |
| defect that leades to albinism | lack of tyrosinase |
| Central canal of bone includes | vein, artery, and nerve |
Created by:
kelboarder89
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