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Biochem Exam

NAD Vitamin Niacin (B3)
FAD Vitamin Riboflavin (B2)
TPP Vitamin Thiamine (B1)
CoA vitamin Pantothenate (B5)
Folic Acid Tetrahydrofolate
Pyroxidal Phosphate Pyridoxine (B6)
Vmax max velocity of a rxn
Km concentration of substrate
Kd measure of binding
Competitive Inhibitor binds substrate binding site, decrease rxn rate, increased km
Non-Competitive Inhibitors binds allosteric substrate,
GLUT 1 highly expressed in erythrocytes and high affinity for glucose
GLUT 2 low affinity transporter, liver
GLUT 3 high affinity transporter, brain
GLUT 4 insulin sensitive, adipose and muscle
VIII stimulates platelet degredation, activates 10, activated by thrombin
X stimulates prothrombin to thrombin
III Tissue factor, activates 7
VII beginas cascade based on trauma
XIII crosslinks (hard clot formation)
V activated by thrombin, cofactor to 10 to change prothrombin to thrombin
Fibrinogen with thrombin (2a) causes fibrin to form soft clot
Thrombin activates 11
coagulation cofactors 8 and 5
Externsic Pathway 3-7-10
Intrinsic 12-11-9 (with 8)-10
aPTT intrinsic and common pathway
PTT extrensic and common pathway
Hemophilia A deficiet factor 8
Hemophilia B deficit factor 9
Heparin blocks coagulation by inhibiting factor 2 (AKA Thrombin)
Inhibitors of Coagulation Protein S, C, Serpins, Heparin
type I collagen main type CT, bone, teeth, encapsulated organs resist force, tension and stretch
type II collagen cartilage resists intermittent pressure
Type III Collagen found in reticular fibers scaffolding for specialized cells
Type IV Collagen basement membrane suppoer and filtration
Type VII Collagen skin, eye, etc connects basement membrane to ECM
Mast Cells allergies-secrete histamine and heparin
Plasma Cells produce antiboides, made in marrow
Anaphylaxis hypersensitivity to histamine, drop in BP and close airways
histamine increases contratcion of vessels, permeability of vessels and mucous production
MMP (metalloprotesases) breaksdown damaged fibers via phagocytosis
apocrine sweat glands 3 A's:axilary, anal, aerolar ducts secrete via exocytosis
eccrine sweat glands watery secretion and ducts
sebaceous glands oily substance to hair follicles whole cells into gland
Pilosebaceous unit hair shaft, sebaceous gland, arrector pili muscle, hair follicle and hair root
Basal Cell Carcinoma arises from follicular bulge of hair
defect that leades to albinism lack of tyrosinase
Central canal of bone includes vein, artery, and nerve
Created by: kelboarder89