Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Acids, Bases,Buffer

Medical Biochemistry

QuestionAnswer
4 Common Causes of Respiratory Acidosis Asthma Bronchitis Obesity Sedatives/ Anesthetics
Buffers and the Henderson-Hasselbalch equation -Resists changes in pH -Weak acid + Conjugate base; Most effective in pH range closely surrounding pKa of the acid; -pH= pKa+log[A]/[HA]
Lungs and Kidneys working together on pH -Lungs control carbon dioxide and can raise or lower via hypo/hyperventilation if kidneys fail or aren’t performing properly –Kidneys control Carbonate (HCO3) and can also compensate for lungs if not functioning properly, but takes longer
Effect on pH of increased [H] -pH is decreased –pH=log[H] or 1/[H]
3 common causes of respiratory alkalosis -Anxiety/Pain –High Altitude –Mechanical hyperventilation
pH > pKa pH < pKa pH = pKa -Base form predominates –Acid form predominates –[A]=[HA]; 50% acid dissociated
Buffers and the pH of blood and interior of cell Blood=CO2/Bicarbonate (pH:7.35-7.45) – CO2 g <> CO2 d + H2O <> H2CO3 <> H + HCO3 -*Hemoglobin also acts as a buffer Cell= Organic phosphate (pH: 6.9-7.4; avg pH 7.1) *inorganic phosphate model H3PO4H2PO4<7.2>HPO4<12.6>PO4
pH of Blood when OH is added/decreased and when H is added/taken away -Addition of OH and H effect [HCO3] – Adding OH increases [HCO3], increasing pH and vice versa – Adding H decreases [HCO3], decreasing pH and vice versa * 1 HCO3 consumed per H added
Open system used to buffer blood (H-H of blood) CO2 and H2CO3 <> H + HCO3 are controlled independently –concentration of one does not affect the other in a direct way –pH change is less dramatic *pH-610 + log[HCO3]/[CO2 d]
Hypoventilation vs Hyperventilation -hypoventilation slows respiratory rate, raising Pco2 and lowering pH –hyperventilation increases respiratory rate, lowering Pco2 and raising pH
CO2 and HCO3 acid-base imbalances and the process of occurrence -CO2 imbalances=respiratory acidosis and alkalosis –HCO3 imbalances= Metabolic acidosis and Alkalosis – Alkalemia= process of raising the pH –Acidemia= process of lowering the pH
4 common causes of metabolic alkalosis -Acute alkali administration (antacids) –Vomiting –Gastric aspiration –Diuretics
3 common causes of metabolic acidosis -Renal failure –Methanol poisoning –Diabetic ketoacidosis
Created by: MastamikeOD