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visceral liver

visceral liver pathology

This is considered the end-stage of chronic liver disease cirrhosis of the liver
what are the stages of chronic liver disease? necrosis, fibrosis, vascular destruction/derangement, regenerative nodules, destruction of the normal liver architecture, diffuse involvement of the whole liver
alcohol, viral, biliary diseases, and hemochromatosis are all risk factors for what? cirrhosis of the liver
loss of functional liver parenchyma causes what? ascites, hypoalbuminemia, clotting abnormalities, jaundice, risk of infection, portal hypertension, endocrine abnormalities, hepatocellular carcinoma
portal hypertension is a hallmark for what? cirrhosis of the liver
what is the most common clinical symptom for liver problems? jaundice
yellow discoloration of conjunctiva and mucous membrane icterus
icterus causes what? hyperbilirubinemia and pruritus
what are the three types of jaundice? hemolytic, hepatic, obstructive
hemolytic jaundice presents with what? increased bilirubin in serum but not in urine, urine color is normal
hepatic jaundice presents with what? increased bilirubin in serum and bilirubin is present in urine (dark urine)
hepatic jaundice is also known as what? cirrhosis
hemolytic jaundice is also known as what? hemolytic anemia
obstructive jaundice presents with what? increased bilirubin in serum, dark urine, pale stool
obstructive jaundice is also known as what? cholestasis (gall bladder disease)
Physiological jaundice presents with what? mild jaundice from 2nd to 8th day after birth due to the result of immaturity of the liver enzyme system
neonatal pathological jaundice is also known as what? kernicterus
A severe neurological condition that is associated with very high levels of unconjugated bilirubin in the blood and brain cuasing cerebral dysfunction kernicterus
patient presents with lethargy, convulsions, hearing loss, mental retardation kernicterus
An inherited, mild, chronic unconjugated hyperbilirubinemia that is casued by impaired clearance of bilirubin in the absence of any detectable function or structural liver disease Gilbert Syndrome
Intercurrent illness or fasting can affect bilirubin levels how? mildly increase
An inherited, mild, chronic conjugated hyperbilirubinemia that is casued by impaired clearance of bilirubin with depostition of melanin like pigments in the liver (black liver) Dubin-Johnson syndrome
patient presents with mild intermittent jaundice with dark urine dubin-johnson syndrome
does gilbert syndrome present with conjugated or unconjugated hyperbilirubinemia? unconjugated
does dubin-johnson syndrome present with conjugated or unconjugated hyperbilirubinemia? conjugated
familial conjugated hyperbilirubinemia but without liver pigments Rotor syndrome
Familial; self-limited periodic episodes of malaise and itching due to bile stasis in bile canaliculi Benign recurrent intrahapatic cholestasis
This disease is characterized by pruritis and cholestatic jaundice during the last trimester of pregnancy which disappears after delivery cholestasis of pregnancy
what are some complications associated with cholestasis of pregnancy? fetal distress, prematurity or stillbirth
hepatic encephalopathy- high levels of ammonia in the blood and brain fulminant hepatitis
idiopathic, chronic hepatitis with autoantibodies and increased serum immunoglobulins autoimmune hepatitis
idiopathic, chronic condition associated with inflammation and fibrosis that narrows and eventually obstructs the bile ducts primary sclerosing cholangitis (PSC)
excessive absorption and toxic accumulation of iron in hepatocytes, pancreas, joint cavities, heart and skin hereditary hemochromatosis
this disease is autosomal dominant and presens with cirrhosis, cardiomegaly, skin pigmentation, arthropathy and diabetes mellitus hereditary hemochromatosis
in sickle cell anemia and thalassemia and dietary iron overload secondary hemochromatosis
Autosomal recessive, excessive copper deposition in liver and brain Hepatolenticular disease: wilson's disease
patient presents with jaundice, tremors, dysarthria, kayser-fleischer ring in the eyes and spontaneous bone fractures and osteoporosis hepatolenticular disease: wilson's disease
wilson's disease is aka what? hepatolenticular disease
this is caused by acetaminophen, NSAIDS, and some herbal remedies hepatotoxicity: drug induced liver dz
patient presents with high fever and rt quadrant pain, rapid weight loss and hepatomegaly hepatic pyogenic abscess
what are benign hepatic tumors? hepatic adenoma, hepatic hemangioma
common in women of reproductive age gp with h/o oral contraceptives hepatic adenoma
these present mostly as solitary and sharply demarcated masses hepatic adenoma
most common in young children and is asymptomatic or rt hypochondrial pain hepatic hemangioma
this presents as a solitary mass and the etiology is HCV, HBV, alcoholic cirrhosis or hemochromatosis hepatocellular carcinoma
patient presents with jaundice, painful hepatomegaly and cachexia hepatocellular carcinoma
this is cancer arising from the intrahepatic bile ducts and is found in older adults cholangiocarcinoma
patient presents with jaundice, weight loss and itching cholangiocarcinoma
this is due to exposure to vinyl chloride or inorganic arsenic hemangiosarcoma
this disease presents with multiple hemorrhagic nodules microscopically hemangiosarcoma
patient presents with hepatomagaly, jaundice and ascites hemangiosarcoma
Created by: kissukels587