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Histo L3&4
Cell Components and Cell Replication
| Term | Definition |
|---|---|
| Cytology | Study of the anatomy, physiology, pathology and chemistry of the cell |
| Robert Hooke | Discovered and named the cell in 1665 (cellula) |
| Cytosol | Fluid medium within the cell, mainly water and dissolved particles |
| Cytoplasm | Contains fluid and organelles, where energy production and protein synthesis happen |
| Cell Contents | 70% Water, 30% chemicals |
| Chemical Components of Cell | 15% proteins, 4% small molecules, 6% RNA, 2% phospholipids, 1% DNA, 2% polysacharides |
| Plasma Membrane | exomembrane, many functions depend on the plasma membrane |
| Endomembranes | Organelles and nucleus |
| Mitochondrial Core | Internal mitochondrial membrane, double membrane |
| Structure of Plasma Membrane, Lipids | Phospholipid bilayer, cholesterol, glycolipids |
| Structure of Plasma Membrane, Proteins | Structural or signaling, transportation, other basic protein functions |
| Structure of Plasma Membrane, Hydrocarbons | Mainly surface glycoproteins |
| Fluid Mosaic Creation | 1972, Singer and Nicolson |
| Fluid Mosaic Meaning | The cell membrane is fluid and elastic, proteins and lipids can move around |
| Membrane Transport Mechanisms- Diffusion | Passive transport for small nonpolar molecules. From high to low concentrations |
| Membrane Transport Mechanisms- Channel | Passive transport through protein pores that open for ions and small molecules. From high to low concentrations |
| Membrane Transport Mechanisms- Carrier | Passive transport for small polar molecules. From high to low concentrations Moves against the concentration |
| Membrane Transport Mechanisms- Pump | Active transport requiring ATP. Moves against the concentration |
| Membrane Transport Mechanisms- Vesicles | Active transport through endocytosis |
| Endocytosis | Vesicle formation to bring in particles. 2 types |
| Phagocytosis | Cell bringing in solids, Eating |
| Pinocytosis | Cell bringing in liquid, drinking |
| Modifications- Microvilli | On apical (surfaces facing a cavity) surfaces, small finger-like protrusions |
| Modifications- Glycocalyx | Ex: Endothelium, keep cells from sticking to lumen. Carbohydrate coating on the outer surface of membranes. |
| Modifications- Intermembranous junctions | Ex: Epidermal cell's desmosomes. Spot welds two cells together with linker glycoproteins, important for local regulation |
| Mitochondria | Important for energy production |
| Mitochondria Structure | 3 parts. Outer smooth membrane (porous), Matrix (similar to cystsol), Inner rough membrane (many folds) |
| Mitochondria 3 Main functions | Oxidative phosphorylation (ADP to ATP), Respiratory Chain, Krebs Cycle |
| Mitochondrial Reproduction | Autonomous division aka fission |
| What cells lack Mitochondria | Prokaryotes and red blood cells |
| Rough Endoplasmic Reticulum | Surface covered with ribosomes, important for protein synthesis that are being exported. form nuclear membrane |
| Ribosomes |