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Urinary System
histological overview of the urinary system
| Question | Answer |
|---|---|
| What organs are included in the urinary system? | The urinary system includes the kidneys, ureters, bladder, and urethra. |
| What is homeostasis? | Homeostasis is the regulation of internal body conditions. |
| What does erythropoietin do? | Erythropoietin is a hormone that stimulates red blood cell production. |
| What is renin's role in the body? | Renin is an enzyme that regulates blood pressure and volume. |
| How much blood do the kidneys filter per minute? | The kidneys filter approximately 125 mL of blood per minute. |
| How much fluid do the kidneys reabsorb per minute? | The kidneys reabsorb approximately 124 mL of fluid per minute. |
| What is the average daily urine production? | The average urine output is approximately 1500 mL per day. |
| Where are the kidneys located? | The kidneys are located in the posterior abdominal cavity |
| What is the hilum of the kidney? | The hilum is the entry and exit point for the ureter and vessels. |
| What is the renal sinus? | The renal sinus is a cavity at the hilum of the kidney. |
| What is the renal pelvis? | The renal pelvis is the expanded upper end of the ureter. |
| What are major calyces? | Major calyces are 2-3 branches from the renal pelvis. |
| What are minor calyces? | Minor calyces are smaller branches from major calyces. |
| What is the kidney cortex? | The kidney cortex is the outer layer with a granular, dark appearance. |
| What is the kidney medulla? | The kidney medulla is the inner layer containing renal pyramids. |
| What are renal pyramids? | Renal pyramids are 8-12 striated structures in the medulla. |
| What is a nephron? | A nephron is the functional unit of the kidney, with approximately 1 million per kidney. |
| What does the renal corpuscle do? | The renal corpuscle filters blood and consists of a glomerulus and Bowman's capsule. |
| What is a glomerulus? | A glomerulus is a network of fenestrated capillaries in the renal corpuscle. |
| What surrounds the glomerulus in the kidney? | Bowman's capsule surrounds the glomerulus as a double-walled structure. |
| What are podocytes? | Podocytes are specialized cells enveloping glomerular capillaries with large processes resembling tentacles. |
| What captures filtrate in Bowman's capsule? | The urinary space captures filtrate in Bowman's capsule. |
| What forms filtration slits in podocytes? | Pedicels, smaller processes extending from podocytes, form filtration slits measuring 25-30 nm wide. |
| What does the glomerular basement membrane (GBM) do? | The GBM restricts particles larger than 4 nm or 70 kDa during filtration. |
| What are fenestrae in endothelial cells? | Fenestrae are openings approximately 75 nm wide in endothelial cells. |
| What makes up the filtration barrier in kidneys? | The filtration barrier consists of multiple layers from capillary to urinary space. |
| What role do mesangial cells play in kidneys? | Mesangial cells provide support between endothelial cells and podocytes, secrete immune mediators, perform phagocytosis, and influence blood flow through their contractile function. |
| Where does ultrafiltrate absorption occur in nephrons? | Ultrafiltrate absorption occurs in the proximal convoluted tubule (PCT), which absorbs 80% of ultrafiltrate including Na+ and H2O. |
| What does aldosterone regulate in kidneys? | Aldosterone regulates sodium (Na+), chloride (Cl-), and water balance. |
| Which hormone promotes water reabsorption in kidneys? | Antidiuretic hormone (ADH) promotes water reabsorption in kidneys. |
| How does urine travel from kidneys to bladder? | Urine travels through ureters via peristaltic contractions to reach the bladder. |
| Where does erythropoietin come from in kidneys? | Erythropoietin is secreted by interstitial cells within kidney tissue. |
| What type of epithelium lines ureters and bladder? | Transitional epithelium lines ureters and bladder for flexibility during urine storage and transport. |