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Bacterial Inhibitons

QuestionAnswer
Chloramphenicol Inihibits bacterial protein sythesis by blocking peptidyltransferase
Streptomycin Inhibits prokaryotic peptide chain initiation, also cuases misreading
Tetracycline Inhibits prokaryotic aminoacyl-tRNA binding to the ribosomal small unit
Neomycin Similar activity to streptomycin
Erythromycin Inhibits prokaryote translocation through the large ribosomal subunit
Fusidic acid Similar to erythromycin only by preventing EF-G from dissociating from the large subunit
Puromycin Resembles amino acyl-tRNA inteferes with peptide transfer resulting in premature termination in eukaryotes and prokayotes
Diptheria toxin Catalyzes ADP-ribosylation and inactivation of eEF-2
Ricin Found in castor beans, catalyze cleavage of the eukaryotic large subunit rRNA
Cyclohexamide Inhibits eukaryotic peptidyltransferase
Adriamycin (treatment of tumors) Intercalate double stranded DNA
Bloom's syndrome Defects in DNA helicase (chromosome breaks)
Faconi's Anemia strand breaks
Created by: 138401073
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