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NURS 319: Pulmonary

Chapters 20 & 21: Pulmonary and Respiratory Systems

QuestionAnswer
what parts of the body are involved with breathing? diaphragm, abdominal muscles, lungs, throat
what is inhaled in breathing? oxygen
what is exhaled in breathing? carbon dioxide
what innervates the diaphragm? C3, C4, C5
what does it mean for the ability to breathe if there is damage to the spinal cord? it can be severely impacted and even cause death
protective mechanism in the lungs that traps inhaled particles and moves them up to the upper airway to be coughed out mucociliary apparatus
what impacts the mucociliary apparatus and how? respiratory infections and smoking; increased viscosity of mucus
what are retractions? pulling inward of soft tissues between ribs upon inhalation
what are adventitious breath sounds? superimposed over normal breath sounds; crackles, wheezes, rhonchi, friction rub
how is breathing controlled? automatic, controlled by respiratory center in base of brain
process of diffusion in the airways oxygen in and carbon dioxide out, acid-base balance, ATP to mitochondria
where does gas exchange occur? alveoli
SaO2 oxygen saturation of hemoglobin
oxyhemoglobin Hgb with attached O2
erythropoietin secreted by kidneys when BP is low
airway resistance resistance in respiratory tract to airflow during exhalation and inhalation
compliance of the lungs elasticity, expandability, distendibility
dyspnea difficulty breathing
expectoration expulsion of mucus, sputum, or fluids from the respiratory tract by coughing or clearing one's throat
hemoptysis coughing up blood (from lower respiratory)
ventilation breathing and its track; expiration: breathing/ pushing out
perfusion flow of blood around alveoli through capillaries
hypoxia low oxygen in blood
how does hypoxia affect the vessels? pulmonary vasoconstriction
hypercapnia higher levels of CO2 in blood
how does hypercapnia affect the vessels? vasoconstriction
new stimulus to breathe when the body experiences chronic hypercapnia (allostatic overload) hypoxia
atelectasis collapse of small # of alveoli
common causes of atelectasis sedation, shallow breathing, decreased respiratory rate, pneumonia
anoxia no oxygen
carbon monoxide poisoning hemoglobin has higher affinity for carbon dioxide than oxygen. hemoglobin picks up more co2 than o2. body does not get o2 to muscles, lungs, etc. and gets sick/ shuts down but hemoglobin will continue to carry co2 instead
why does a person with carbon monoxide poisoning stay pink in color? formation of carboxyhemoglobin
respiratory failure failure to oxygenate blood or remove carbon dioxide
what would cause a hypoxemic failure? pulmonary edema, pneumonia PaO2 less than 60 mmHg
what would cause a hypercapnic failure? COPD, asthma PaCO2 greater than 50 mmHg
chest X-rays takes contrasting image of chest
pulse oximetry measures level of O2 saturation
arterial blood gases o2 and co2 levels in blood
CT scan and MRI more detailed image
bronchoscopy scope down to 2nd generation bronchioles
thoracentesis remove fluid or air from around the lungs
sputum cultures taking sample of patient mucus and running tests on it
V/Q scan ventilation and perfusion
what does mismatch V/Q show? air cannot flow into an alveolus or blood flow around alveolus is altered
what is the most common disorder that a V/Q mismatch indicate? pulmonary embolus
pulmonary function test spirometry + lung volumes and air flow
what is the difference between acute and chronic rhinitis? length/frequency of inflammation acute: 2-4 days
symptom of bacterial rhinitis antibiotics work, more gradual onset
symptom of viral rhinitis antibiotics do not work, more rapid onset
rhinitis inflammation of mucus membranes
sinus infection inflamed sinuses that drain into membranes
what symptom of a sinus infection would be worrisome and why? (requires hospitalization) altered mental status/ dizziness indicates that infection has spread to brain
usual causative agent for bacterial acute pharyngitis group A beta hemolytic streptococcus
why do we worry about group A beta hemolytic streptococcus can cause many life-threatening diseases affects heart, kidneys, lungs
common symptoms of an infection caused by group A beta hemolytic streptococcus red, swollen tonsils white exudate on tonsils enlarged lymph nodes
how do we diagnose bacterial pharyngitis throat culture/ rapid screening
is there a difference between acute pharyngitis and acute tonsilitis acute tonsilitis can be caused by EBV, adenovirus, Herpes simplex virus, cytomegalovirus
causes and symptoms of tonsilitis sore throat, fever, difficulty swallowing, erythema, quinsy, swelling of pharynx
inflammation of the epiglottis epiglottitis
key symptoms of acute epiglottitis infection and inflammation, ABGs, steeple sign, inflamed/red/stiff/ swollen epiglottis
what must you NOT do when you see a patient with symptoms of acute epiglottitis keep them calm and do NOT do a throat swab
what preventative measure can you take to avoid acquiring acute epiglottitis getting antibiotics in system as soon as possible when sick
what is acute bronchitis inflammation of bronchi + bronchioles
when do we commonly see acute bronchitis fall and winter
symptoms for acute bronchitis sore throat, nasal discharge, muscle aches, persistent cough, fever, sputum (clear, yellow, green, blood-tinged)
diagnostic criteria for chronic bronchitis lasts longer than 3 months for 2 consecutive years or more
which part of the lung is predominately affected by bronchitis bronchial tubes
pathophysiology of bronchitis inflammatory response to pathogen or irritant
types of pneumonia + key characteristics community acquired pneumonia: spread rapidly hospital acquired pneumonia: within 48 hours of admission aspiration pneumonia: bacteria in oropharynx mycoplasma pneumonia: walking pneumonia
pathophysiology of pneumonia inhalation of droplets
symptoms of pneumonia cough, fever/chills, dyspnea, chest pain, hemoptysis, myalgias
part of the lung predominately affected by pneumonia lung tissue
how is pneumonia diagnosed chest X-ray and sputum culture
difference between latent and active tuberculosis latent: dormant active: showing symptoms
tuberculosis pathophysiology inhalation of airborne droplets
how do you test for TB? skin test + sputum culture
next test to verify positive TB? chest X-ray
what other issues can TB cause? scrofula, Pott's disease, Addison's disease
symptoms of active TB cough, hemoptysis, weight loss, night sweats
mantoux test and positive looks skin is viewed immediately then 72 hours later skin splotches bigger than 20mm
restrictive lung diseases + examples decrease in total lung capacity pulmonary fibrosis, thoracic cage deformity
obstructive lung disease + examples increased resistance to air flow emphysema, COPD, asthma
primary factor for lung disease smoking
secondary (major) risk factor for lung disease occupational and environmental exposures
when teaching a patient about lung diseases, what is a major focus of education? try to stop smoking and avoid exposure if you can
bronchodilation dilation of bronchi/ bronchioles
what part of the nervous system causes bronchodilation sympathetic ANS
receptors responsible for bronchodilation beta-2 adrenergic receptors
bronchoconstriction constriction of bronchi/ bronchioles
what part of the nervous system causes bronchoconstriction parasympathetic ANS
chemical mediators that lead to bronchoconstriction leukotrienes histamine
where is the pleural membrane lines chest cavity, envelopes lungs
why is the pleural membrane important how lungs expand appropriately
the pleural membrane is under a ______ ______ pressure which allows the lungs to inflate easily negative intrathoracic
accumulation of fluid in the pleural space pleural effusion
accumulation of air in the pleural space pneumothorax
how does chronic hypercapnia affect chemoreceptors in the brain headache, drowsiness, intellectual impairment
what is the level of co2 that is considered hypercapnia greater than 45 mmHg
when a patient has chronic hypoxia, what hormone is released to stimulate the production of red blood cells erythropoietin
normal po2 level 75 to 100 mmHg
po2 level that indicates blood is not perfusing tissues less than 60 mmHg
less perfusion of blood to tissues = increased ventilation
increased ventilation = production of erythropoietin
production of erythropoietin = pulmonary vasoconstriction
pulmonary vasoconstriction = pulmonary hypertension
pulmonary hypertension = cor pulmonale
symptoms you would expect to see in hypoxia fatigue, clubbing, cyanosis
what is clubbing and what causes it rounding of fingernails open ended capillaries from hypoxia
what is cyanosis and what causes it blue discoloration of the skin + membranes; excessive concentration of deoxygenated hemoglobin
3 characteristics to asthma hyperreactive airway, reversible airway constriction, inflammatory changes
one thing about asthma that sets it apart from other respiratory illnesses bronchial remodeling
how do chronic asthma attacks affect the tissues of the lungs leads to swelling
which inflammatory cells play a role in asthma? histamine, T cells, IgE, leukotrienes, eosinophils
symptoms of asthma prolonged expiration, wheezing, cough, dyspnea, chest tightness
diagnostics of asthma FVC/ FEV1 ratio diminishes
classifications of asthma mild intermittent: flares mild persistent: 2x/wk, interferes with life, persistent bronchodilation despite reversal attempts moderate persistent: receptors saturated severe persistent: continuous symptoms
what part of the lung does chronic bronchitis affect? mucus in bronchioles
chronic bronchitis main issue hypoxia
why would a person with chronic bronchitis have elevated hemoglobin body trying to increase oxygen delivery to lungs
chronic bronchitis symptoms clubbing, cough, vasoconstriction, mucus + edema
what is "blue bloater" cyanosis and inflammation
what part of the lung does emphysema affect alveoli
emphysema main issue hypercapnia
what is "pink puffer" carbon monoxide overload thin and flat diaphragm
emphysema symptoms barrel-shaped chest, prolonged exhalation
how can chronic bronchitis and emphysema lead to cor pulmonale overworking right side of heart to compensate
how COPD can lead to a change in respiratory drive body adapts to amount of oxygen available
what would happen if we give a patient too much oxygen and increase their oxygen saturation to 100% with FiO2? reperfusion injury equivalent; body would be unable to handle it
pathology of bronchiectasis bronchiole wall destroyed and replaced by fibrous tissues
apnea reduction in airflow by 90% for at least 10 seconds
difference between obstructive sleep apnea and central sleep apnea obstructive: upper airway tissues central: loss of respiratory drive from brainstem
symptoms of sleep apnea loud snoring, choking/gasping during sleep, unrestful sleep, daytime sleepiness
sleep apnea diagnosis sleep study
pneumothorax air in pleural space
primary pneumothorax tall, young men (30s)
secondary pneumothorax long-term emphysema
traumatic pneumothorax penetrating wound to ribcage
tension pneumothorax compression
latrogenic pneumothorax complication of medical procedures
symptoms of pneumothorax chest pain, dyspnea, increased respiratory rate
diagnosis of pneumothorax chest X-ray, CT scan, pulse oximetry + ABGs
pleural effusion fluid in pleural cavity
pleural effusion symptoms dyspnea, tachypnea, sharp chest pain, diminished breath sounds
pleural effusion diagnosis chest X-ray
types of environmental lung disease coal worker, asbestosis, silicosis
scoliosis curvature of the spine (sideways)
kyphosis curvature of the spine (hunchback)
how do scoliosis and kyphosis lead to restriction in the lungs ribcage can shift and crush lungs
idiopathic pulmonary fibrosis injury to lung tissue by an unidentified agent
pulmonary edema build up of fluid + swelling
pulmonary edema symptoms swelling, weight gain, anorexia
most common cause of pulmonary edema left ventricular heart failure
how can a DVT lead to pulmonary embolism DVT can break off and travel through bloodstream to lungs
how a V/Q mismatch occurs perfusion or ventilation is hindered and now ratio does not match
how does pulmonary hypertension lead to cor pulmonale R. ventricle hypertrophies and eventually fails because it is overworked
pathology of adult respiratory distress syndrome sudden, progressive pulmonary edema
who do we see ARDS occur in? critically ill patients
ARDS symptoms hypoxemia that does not improve PO2 less than or equal to 50 mmHg PCO2 less than or equal to 50 mmHg
Created by: lcorlew1
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