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Immune Responses
PATHO TEST 2
| Question | Answer |
|---|---|
| Type I | Anaphylactic Hypersensitivity - most severe form/immune mediated-rxn - Immediate rxn - mediated by antibodies - occurs on re-exposure to a specific antigen Ex: Anaphylaxis |
| Type I Side Effects | BP drop swollen tongue and throat airway constriction weak pulse nausea dizziness angiodema |
| Type II | Cytotoxic Hypersensitivity - system mistakes normal constituent of the body as foreign Ex: Blood transfusion |
| Type II Side Effects | Fever Chills Urticaria |
| Type III | Immune Complex Hypersensitivity - immune complexes formed when antigens bind to antibodies Ex: Systemic: Lupus/Localized: Rheumatoid arthritis |
| Type IV | Delayed type hypersensitivity - cellular hypersensitivity - 24-72 hours after exposure to allergen Ex: Mantoux test for TB |
| Type III SIde Effects | Rash Athritis Fever Proteinuria |
| Type IV Side Effects | Malaise Pruitis Erythma Urticaria Paresthesia Angioedema Wheezing |