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Patho chap 31
Infection, inflammation & cirrhosis of the liver
| Question | |
|---|---|
| hepatocytes | the functional cells of the liver and forms a yellow green substance called bilirubin |
| what is enterohepatic recycling? | bile salts reabsorbed from ileum recycled back to liver |
| glycogenesis | the breakdown of glycogen to glucose - 1- phosphate |
| glucogenesis | a process that transforms non carbohydrate substrates into glucose |
| glycogen synthesis | carbohydrates |
| hematologic role | synthesizes fibrinogen - helps stops bleeding synthesizes thrombopoietin for platelet synthesis |
| endocrine role | responds to glucagon and produces insulin - like growth factor 1 |
| detoxification | ingested substances and drugs portal vein brings venous drainage from GI tract to liver |
| hyperbilirubinemia leads to what | jaundice |
| pre haptic jaundice | excess RBC hemolysis |
| intra hepatic jaundice | hepatocellular injury |
| post hepatic jaundice | bile duct obstruction |
| the most common cause of biliary obstruction is.. | cholestasis and hyperbilirubinemia |
| choelstasis | conjugated bilirubin backs up |
| what are common risk factors for liver disease? | excessive alcohol and viral hepatitis |
| list common symptoms of liver disease | jaundice and yellowing in sclera, nausea/ vomitting, weight loss, abdominal distention |
| what does NAFLD stand for and what is it? | non alcoholic fatty liver disease --> fatty buildup in liver |
| NaSH is an extreme form of NAFLD leading to scarring and inflammation of the liver. It can also lead to what? | liver cancer and cirrhosis |
| What is the name of the disorder for someone who uses alcohol every day for 10 years and is permanent? | alcoholic liver disease |
| what is the name of the disorder for someone who uses alcohol and they have reversible symptoms that resolve when they stop drinking alcohol? | acute liver disease/ acute hepatitis |
| the first cellular change in alcoholic liver disease is called | steatosis |
| the fat accumulates in and around the cells leading to what | inflammation |