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Patho chap 31
Infection, inflammation & cirrhosis of the liver
Question | |
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hepatocytes | the functional cells of the liver and forms a yellow green substance called bilirubin |
what is enterohepatic recycling? | bile salts reabsorbed from ileum recycled back to liver |
glycogenesis | the breakdown of glycogen to glucose - 1- phosphate |
glucogenesis | a process that transforms non carbohydrate substrates into glucose |
glycogen synthesis | carbohydrates |
hematologic role | synthesizes fibrinogen - helps stops bleeding synthesizes thrombopoietin for platelet synthesis |
endocrine role | responds to glucagon and produces insulin - like growth factor 1 |
detoxification | ingested substances and drugs portal vein brings venous drainage from GI tract to liver |
hyperbilirubinemia leads to what | jaundice |
pre haptic jaundice | excess RBC hemolysis |
intra hepatic jaundice | hepatocellular injury |
post hepatic jaundice | bile duct obstruction |
the most common cause of biliary obstruction is.. | cholestasis and hyperbilirubinemia |
choelstasis | conjugated bilirubin backs up |
what are common risk factors for liver disease? | excessive alcohol and viral hepatitis |
list common symptoms of liver disease | jaundice and yellowing in sclera, nausea/ vomitting, weight loss, abdominal distention |
what does NAFLD stand for and what is it? | non alcoholic fatty liver disease --> fatty buildup in liver |
NaSH is an extreme form of NAFLD leading to scarring and inflammation of the liver. It can also lead to what? | liver cancer and cirrhosis |
What is the name of the disorder for someone who uses alcohol every day for 10 years and is permanent? | alcoholic liver disease |
what is the name of the disorder for someone who uses alcohol and they have reversible symptoms that resolve when they stop drinking alcohol? | acute liver disease/ acute hepatitis |
the first cellular change in alcoholic liver disease is called | steatosis |
the fat accumulates in and around the cells leading to what | inflammation |