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NURS 319: Liver

NURS 319: Chapter 31 Infection, Inflammation and Cirrhosis of the Liver

QuestionAnswer
function cells of the liver hepatocytes
hepatocytes form bilirubin
enterohepatic recycling bile salts reabsorbed from ileum recycled back to liver
bilirubin metabolism RBC - heme + globin - iron + porphyrin - unconjugated bilirubin - liver - conjugated bilirubin - bile - urine
fat metabolism bile to intestine - fats - triglycerides - portal vein + liver - liver synthesizes cholesterol
protein metabolism albumin - osmotic pressure - deaminate metabolized amino acids
carbohydrate metabolism glycogenolysis + gluconeogenesis + glycogen synthesis
hematological role fibrinogen + thrombopoietin
endocrine role insulin-like growth factor 1
detoxification portal vein brings venous drainage from GI tract to liver
other functions stores vitamins, iron, copper
hyperbilirubinemia leads to jaundice
3 possible causes of elevated bilirubin levels 1. excessive RBC hemolysis- prehepatic jaundice 2. hepatocellular injury - intrahepatic jaundice 3. bile duct obstruction - posthepatic jaundice
most common causes of biliary obstruction cholestasis and hyperbilirubinemia
what are common risk factors for liver disease? enzymes, alcohol damage, hepatocellular injury
common symptoms for liver disease and why they may have the symptom RUQ pain (hepatomegaly, hyperbilirubinemia), spider angioma (fine capillaries fan out), caput medusa (dilated veins in abd. area), ascites (serous fluid between tissues and organs of abd. cavity), steatorrhea (fat excretion in stool- unable to digest)
NAFLD non-alcoholic fatty liver disease fatty build-up liver
extreme form of NAFLD NASH; leads to scarring and inflammation of the liver; can lead to hepatic encephalopathy
alcohol liver disease someone who uses alcohol everyday for 10 years; permanent disease
fatty liver disease uses alcohol, has reversible symptoms- resolve when they stop drinking
steatosis first cellular change in alcoholic liver disease
steatohepatitis fat accumulates in and around cells
Created by: lcorlew1
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