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Rickettsia 3
Microbiology 1 - Rickettsia 3
| Question | Answer |
|---|---|
| Rocky Mountain Spotted Fever | Rickettsia Rickettsii |
| R. Rickettsii | 1st recognized as Rickettsial disease |
| R. Rickettsii transmission | to humans by ticks |
| R. Rickettsii incubation | 3-4 days |
| R. Rickettsii Sx: | fever, headache, - rash develops extremities to trunk (rash due to damage of blood vessels) |
| R. Rickettsii mortality w/no prompt treatment | 5-80% |
| Trench Fever | Bartonella/Rochalimaea/Rickettsia Quintana |
| Trech Fever aka | shinbone fever, 5 day fever, Polish-Russian Intermittent Fever, His-Werner Disease |
| Trench fever predisposing factor | stress |
| trench fever | culturable |
| trench fever 1st seen in | WWI |
| trench fever Sx | leg pain, exhaustion, depression |
| Bartonellosis | Bartonella Bacilliformis |
| Bartonellosis | 2 forms |
| 2 forms | Oraya Fever (Carrion's Disease) & Verruga Peruana |
| Oroya Fever | Acute fatal fever w/severe anemia, develops in those w/no immunity |
| Verruga Peruana | chronic, nonfatal skin disease, in those w/partial immunity |
| Bartonellosis incubation | week to months |
| Ehrilichiosis | Ehrlichia Canis |
| Ehrlichia Canis | orginally in dogs |
| Ehrilichiosis caused by | E. Canis & E. Chaffeenis |
| Ehrilichiosis spread by | dog ticks & ioxedes (ticks that spread lyme disease) |
| Ehrilichiosis Sx: | fever, headache, hepatitis, myalgia, NO RASH |
| Ehrilichiosis Dx: | ehrlichial intracytoplasmic inclusions in WBCs |
| Q-Fever | Coxiella Burnetti |
| Q stands for | Query |
| Q-Fever survives | outside cells |
| Q-Fever transmitted by | droplet route & ticks |
| Q-Fever survives in | wool, dried blood, water & milk |
| Q-Fever has 2 forms | large & small |
| Q-Fever enters human cells via | phagocytosis |
| Q-Fever multiplies in | phagosomes |
| Q-Fever affects | various parts of the body |
| Q-Fever seen in areas | that raise cattle & sheep |
| Q-Fever killed by | Flash Pasteurization (81degrees C for 15 seconds) |
| Q-Fever Sx: | headache, chills, malaise, sweats (similar to primary atypical pneumonia) |
| Q-Fever incubation | 18-20 days |
| Q-Fever Treatment | tetracycline & Fluoroquinolone |
| Q-Fever leaves | lifelong immunity |
| Q-Fever has | vaccine available |
| Untreated Q-Fever | can go into remission - cortisone can reactivate |
| Q-Fever chronic cases | endocarditis & valve infections (can be fatal) |