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Rickettsia 3

Microbiology 1 - Rickettsia 3

Rocky Mountain Spotted Fever Rickettsia Rickettsii
R. Rickettsii 1st recognized as Rickettsial disease
R. Rickettsii transmission to humans by ticks
R. Rickettsii incubation 3-4 days
R. Rickettsii Sx: fever, headache, - rash develops extremities to trunk (rash due to damage of blood vessels)
R. Rickettsii mortality w/no prompt treatment 5-80%
Trench Fever Bartonella/Rochalimaea/Rickettsia Quintana
Trech Fever aka shinbone fever, 5 day fever, Polish-Russian Intermittent Fever, His-Werner Disease
Trench fever predisposing factor stress
trench fever culturable
trench fever 1st seen in WWI
trench fever Sx leg pain, exhaustion, depression
Bartonellosis Bartonella Bacilliformis
Bartonellosis 2 forms
2 forms Oraya Fever (Carrion's Disease) & Verruga Peruana
Oroya Fever Acute fatal fever w/severe anemia, develops in those w/no immunity
Verruga Peruana chronic, nonfatal skin disease, in those w/partial immunity
Bartonellosis incubation week to months
Ehrilichiosis Ehrlichia Canis
Ehrlichia Canis orginally in dogs
Ehrilichiosis caused by E. Canis & E. Chaffeenis
Ehrilichiosis spread by dog ticks & ioxedes (ticks that spread lyme disease)
Ehrilichiosis Sx: fever, headache, hepatitis, myalgia, NO RASH
Ehrilichiosis Dx: ehrlichial intracytoplasmic inclusions in WBCs
Q-Fever Coxiella Burnetti
Q stands for Query
Q-Fever survives outside cells
Q-Fever transmitted by droplet route & ticks
Q-Fever survives in wool, dried blood, water & milk
Q-Fever has 2 forms large & small
Q-Fever enters human cells via phagocytosis
Q-Fever multiplies in phagosomes
Q-Fever affects various parts of the body
Q-Fever seen in areas that raise cattle & sheep
Q-Fever killed by Flash Pasteurization (81degrees C for 15 seconds)
Q-Fever Sx: headache, chills, malaise, sweats (similar to primary atypical pneumonia)
Q-Fever incubation 18-20 days
Q-Fever Treatment tetracycline & Fluoroquinolone
Q-Fever leaves lifelong immunity
Q-Fever has vaccine available
Untreated Q-Fever can go into remission - cortisone can reactivate
Q-Fever chronic cases endocarditis & valve infections (can be fatal)
Created by: JYarger