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Inflammation, Part 2

TermDefinition
Leukotrienes Family of lipid-based inflammatory mediators produced by leukocytes through the oxidation of arachidonic acid
Bradykinin Peptide in the kinin cascade that promotes inflammation by causing vasodilation, increasing capillary permeability and stimulating prostaglandin release
Histamine Chemical released by mast cells that mediates the inflammatory response through vasodilation, increased capillary permeability, and increased bronchial secretions
Prostaglandins Group of lipids that sensitize nerves to pain, regulate blood clotting, and stimulate uterine contractions
Hyperemia Increased blood flow
Cardinal signs of inflammation Redness (rubor or erythema), swelling (edema), heat, pain, and, in some cases, loss of function
Malaise General feeling of being unwell
Leukocytosis High white blood cell (WBC) count
Erythrocyte Sedimentation Rate Measurement of how quickly red blood cells (RBCs) descend to the bottom of a test tube
Differential white blood cell count Measurement of the percentages of each type of leukocyte: neutrophils, eosinophils, basophils, lymphocytes, and monocytes
C-reactive protein Liver protein used as an indicator of inflammation
CK-MB Creatine kinase isoenzyme released by injured heart muscle
ALT Alanine transaminase, a liver enzyme that is elevated in damaged liver tissue
Granuloma Small, localized area of inflammation that contains an aggregate of macrophages
Fibroblast Type of connective tissue cell that produces fibers such as collagen
Collagen Strong thick protein fiber found in many types of connective tissue
Rheumatoid arthritis Chronic, inflammatory, autoimmune disorder in which the body attacks its own joints
Perforation Hole that develops through the wall of a body organ
Aspirin Acetylsalicylic acid; a synthetic NSAID based on a willow bark extract that reduces pain, fever, inflammation, and platelet activation
Reye's syndrome Poorly understood condition that causes confusion and swelling of the liver and brain; children taking aspirin during their recovery from viral infections are especially susceptible
Created by: KES-HFHS
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