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Pain, Part 1
| Term | Definition |
|---|---|
| Somatic pain | Type of pain felt in skin, muscles, joints, and bones that is conducted by sensory nerves |
| Visceral pain | Type of pain that originates in the organs and is carried by the sympathetic nervous system |
| Afferent | Toward |
| Efferent | Away from |
| Nociceptor | Pain receptor |
| Pain threshold | Level of nerve stimulation required for an individual to perceive pain |
| Pain tolerance | Ability to withstand pain or the perception of its intensity |
| Dermatome | Area of the skin innervated by a particular spinal nerve, which maps to a certain area of the somatosensory cortex |
| Reflex | Neural pathway for generating immediate, involuntary responses in the spinal cord that consists of a sensory neuron, an interneuron, and a motor neuron |
| Thalamus | The brain’s information relay station |
| Neospinothalamic tract | Rapid pathway for the signaling of acute pain |
| Paleospinothalamic tract | Slow pathway for the signaling of chronic or dull pain |
| Reticular Activating System (RAS) | Network of nerve pathways in the brainstem connecting the spinal cord, cerebrum, and cerebellum that influences the brain’s awareness of incoming pain stimuli |
| Gate-control theory | Explanation for the attenuation of pain signals in the spinal nerves by other types of sensory inputs |
| Transcutaneous Electrical Nerve Stimulation (TENS) | Therapeutic intervention that increases sensory stimulation at certain sites, blocking pain transmission |
| Histamine | Chemical released by mast cells that mediates the inflammatory response through vasodilation, increased capillary permeability, and increased bronchial secretions |
| Bradykinin | Peptide in the kinin cascade that promotes inflammation by causing vasodilation, increasing capillary permeability and stimulating prostaglandin release |
| Prostaglandins | Group of lipids that sensitize nerves to pain, regulate blood clotting, and stimulate uterine contractions |
| Substance P | Peptide neurotransmitter that modulates pain perception and promotes inflammation |
| Endorphin | Peptide hormone that stimulates the body’s opiate receptors, producing an analgesic effect, also known as 'endogenous morphine' |
| Serotonin | Chemical messenger that regulates mood, sleep, digestion, wound healing, bone health, blood clotting, and libido |