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Neoplasia
| Question | Answer |
|---|---|
| primary target of reactive electrophiles | DNA |
| Phosphorylation of retinoblastoma gene | Promotes cell division |
| Mutation of the following gene is responsible for the transformation of adenoma to adenocarcinoma colon | TP53 |
| Malignancy associated with VHL gene Mutation | Renal Cell Carcinoma |
| Starry Sky appearance in lymphoid tissue seen in | Burkitt Lymphoma |
| Woman with Inherited Mutations in the following gene has substantially higher risk of developing breast and ovarian cancer | BRCA1 |
| Follicular Lymphoma express mutation in the following gene | BCL2 |
| Tumor cells may express the following adhesion molecules whose ligands are found preferentially on the endothelial cells of the target organ | CD44 |
| Type of Apoptotic cell death due to loss of adhesion in normal cells | Anoikis |
| Jak2 is a tyrosine kinase involved in the signaling pathway of …………………… neoplasm | Myeloproliferative |
| Major cytokine which produces the symptoms of cachexia is | TNF-α |
| Primary tumour is more common than metastasis in which of the following | Colon |
| BRCA2 | |
| ERBB2 | |
| BAX | |
| MYC | |
| Lung | |
| Bone |