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Neoplasia
Question | Answer |
---|---|
primary target of reactive electrophiles | DNA |
Phosphorylation of retinoblastoma gene | Promotes cell division |
Mutation of the following gene is responsible for the transformation of adenoma to adenocarcinoma colon | TP53 |
Malignancy associated with VHL gene Mutation | Renal Cell Carcinoma |
Starry Sky appearance in lymphoid tissue seen in | Burkitt Lymphoma |
Woman with Inherited Mutations in the following gene has substantially higher risk of developing breast and ovarian cancer | BRCA1 |
Follicular Lymphoma express mutation in the following gene | BCL2 |
Tumor cells may express the following adhesion molecules whose ligands are found preferentially on the endothelial cells of the target organ | CD44 |
Type of Apoptotic cell death due to loss of adhesion in normal cells | Anoikis |
Jak2 is a tyrosine kinase involved in the signaling pathway of …………………… neoplasm | Myeloproliferative |
Major cytokine which produces the symptoms of cachexia is | TNF-α |
Primary tumour is more common than metastasis in which of the following | Colon |
BRCA2 | |
ERBB2 | |
BAX | |
MYC | |
Lung | |
Bone |