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HIV/AIDS

PATHO TEST 2

QuestionAnswer
HIV/AIDS Human immunodeficiency virus Acquired immunodeficency virus
Retrovirus Carry genetic material in form of RNA
CD4 cells STUDY THIS HIV targets this and it is expressed on glycoprotein surface, T lymphocyte surface, monocyte surface, and dendtritic cells and brain microglia
HIV transmission Blood borne Sexually transmitted virus prevention and education vital No cure
Diagnose blood tests lab tests: - antibody -antigen/antibody - NAT
Stages of HIV 1) primary infection - characterized by intense viral replication - 2 to 3 week window, HIV antibody negative 2) HIV asymptomatic - 6 months rate of viral replication reaches a lower but relatively study state - CONTAGIOUS
Stages continued 3) HIV-symptomatic - # of CD4 T cells declnes gradually 4)AIDS symptomatic - CD4 T cell level drops below 200 cells/mm3 (500-1600)
Manifestations of HIV Penumocystis pneumonia (PCP) - most common, life threatening, opportunistic disease TB/Cytomegalorius (CMV) GI problems: - Esophageal candidiasis - chronic diarhhea - wasting syndrome - 10% loss in body weight accompanied by 30 days of fever/diarhhe
Manifestations continued Kaposi sarcoma (ks) - cancer that develops from the cells that the line the lymph or blood vessels B-cells lymphomas - abnormal b cells HIV encephalopathy - result of damage to the brain by long standing HIV infection Depression
Man. contin. Immune reconsitution inflammatory syndrome (IRIS) - a state of hyperinflammatory response that usually occurs in the first 6 months of treatment of HIV/AIDS
Created by: Mplaster
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