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Properties of Toxins
Microbiology - Properties of Toxins
| side one | side two |
|---|---|
| mostly Gram+, some Gram- | exotoxins |
| extracellular, excreted into medium | exotoxins |
| unstable, denatured above 60 degrees & ultraviolet light | exotoxins |
| most powerful toxins | exotoxins |
| highly specific, some act as neurotoxins or cardiac m. toxins | exotoxins |
| little or no fever produced | exotoxins |
| strong antigenicity; stimulates antibody production & immunity | exotoxins |
| treatment with heat or chemicals; toxoid used to immunize against toxins | exotoxins |
| Ex: botulism, gas gangrene, tetanus, diptheria, staphylococcal food poisoning, cholera, entertoxins, plague | exotoxins |
| mostly Gram+ | endotoxins |
| bound withing bacterial cell wall; released upon death of bacterium | endotoxins |
| lipopolysaccharide complex | endotoxins |
| relatively stable; can withstand several hours above 60 degrees | endotoxins |
| weak, but can be fatal in relatively large doses | endotoxins |
| nonspecific; ache all over systemic effects or local site reactions | endotoxins |
| rapid rise in temperature to high fever | endotoxins |
| weak; recovery from disease often does not produce immunity | endotoxins |
| cannot be converted to toxoid; cannot be used to immunize | endotoxins |
| Ex: Salmonellosis, tularemia, endotoxic shock | endotoxins |