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MCAT BIOCHEM
MCAT
| Term | Definition |
|---|---|
| where does kinesin move to? | + end (toward cell membrane) |
| where does dynein move to? | - end (toward centrosome) |
| motor proteins | kinesin, dyenin, myosin |
| cytoskeletal elements | microtubules, collagen, elastin, keratin |
| signaling proteins | antibodies and peptide hormones |
| isomerase | catalyzes rearrangement of bonds |
| ligase | catalyzes joining of molecules |
| transferase | catalyzes transfer of functional groups |
| lyase | catalyzes breaking a molecule without water |
| hydrolase | catalyzes breaking a molecule with water |
| oxireductase | catalyses transfer of electron between molecules |
| coenzymes | proteins |
| cofactors | ions (can be metals) |
| prosthetic group | cofactors or coenzymes that are bound tight to enzyme |
| holoenzymes | enzyme w/ cofactor or coenzyme |
| apoenzyme | enzyme without cofactor or coenzyme |
| increase in Km | decrease in binding affinity |
| decrease in Km | increase in binding affinity |
| catalytic efficiency | kcat/Km |
| kcat | catalytic efficiency (speed of enzyme) |
| competitive inhibition | Vmax-same, Km-increases |
| uncompetitive inhibition | Vmax-decreases, Km-decreases |
| mixed inhibition | Vmax-decreases, Km-decreases or increases |
| noncompetitive inhibition (type of mixed) | Vm-decreases, Km-stays the same |