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4 methods to control microbes outside of body Sterilization, Disinfection, Sanitation (Decontamination), Antisepsis (Degermation)
Sterilization is To remove or destroy all Bacteria on surfaces
To destroy or remove vegetative pathogens on objects with chemicals or boiling water= except endospores Disinfection
A cleaning technique to remove microbes from objects with soaps and detergents Decontamination or Sanitation
To reduce numbers of microbes on the skin Antisepsis or Degermation
Bactericide does what Destroys bacteria except those of Endospores
Sporicides do what Destroys bacterial endospores
The growth of microbes in blood and tissues that spreads and causes widespread infection is called what Sepsis
Term used to describe the inhibiting of bacterial growth Bacteriostatic
Microbial death is defined as Unable to reproduce under optimal conditions
Factors that effect death rate Population and variety in population, Temp and PH, Amounts of chemicals and Mode of action
Mode of Action is described as How the microbe is destroyed , physical or chemical
4 target areas to cause cell death Cell wall, Cell membrane, Denature Proteins, Affect synthesis process of RNA/DNA
2 categories of microbe control Physical and Chemical
Characteristics of Dry Heat Takes longer than Moist Heat even at higher temps. and Dehydrates cells Incineration and Oven
Characteristics of Moist Heat 3 forms Boiling Water, Hot Water and Steam
The shortest time to kill microbes at a set temp. is known as Thermal Death Time
The lowest temp. required to kill microbes in 10 minutes is Thermal Death Point
Cold temps do what to microbes Slows down the growth rate (Microbistatic) does not destroy them
Term for Dehydrated or Dried thoroughly to preserve Desiccated
3 types of Radiation used for microbial control Gamma, X-Ray, and UV = all are short waves
UV radiation effects cells how Causing an improper bonding of bases in the DNA mainly the T and C
Term for solutions that have solutes dissolved in Alcohol or a Alcohol water Tinctures
High Level Germacides Kill endospores and can be considered sterilization = implants
Intermediate Level Germacides Kill Fugal Spores not bacterial spores, Kills pathogens and viruses= thermoneters
Low Level Germacides Controls only vegetative Bacteria and Fungus and some viruses= furniture
6 ways to control microbes Heat, Cold, Drying, Radiation, Filtration, Osmosis
4 factors in using Chemical agents Population, Material involved, Time, Strength of Agent
Some desirable qualities of germicdes Rapid action, Pentation Ability, Solubility in Solvents, Selective Toxicity, Broad spectrum Action
Freezing and removing water from items to preserve them Lyophilization
Iodophor is Iodine with a surfactant = used as a disinfectant
Surfactants do what Alter the cell membranes permeability , Makes changes to the Lipid Bilayer,
Can UV radiation sterilize NO
Chlorhexidine does what Can be used to clean skin for surgery , is used in mouthwash, Changes the cell membrane and cell wall and targets proteins
Aldehydes Contain the -CHO function group
Modes of Action for Chlorhexidine Disrupt cell membrane and Target proteins ; can be used as a Antisepsis
Modes of Action for Phenol Disrupt membrane and Denature Proteins
Modes of Action for Iodine Denature Proteins , can be used to kill endospores
Modes of Action for Glutaraldehyde Disrupt enzyme function and Altering Amino Acids
What does Surfactants disrupt on microbes Lipid Bilayer and Membrane permeability
Created by: scones and joe
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