Save
Busy. Please wait.
Log in with Clever
or

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever
or

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't know
Remaining cards (0)
Know
0:00
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

cell injury

differences, definition

TermDefinition
virchow's triad slowing of blood stream, changes in the vessel wall, changes in blood itself
cell injury? is defined as a variety of stresses a cell encounters as a result of changes in its internal and external environment.
etiology of cell injury 1. genetic causes 2. acquired causes : hypoxia and ischaemia, physical agents, chemical agents and drugs, microbial agents, immunologic agents, nutritional derangements, ageing, psychogenic diseases, iatrogenic factors , idiopathic diseases
name the physical agents that cause cell injury mechanical trauma, chemical trauma, electricity, radiation, rapid changes in atmospheric pressure
name the immunologic agents that cause cell injury hypersensitivity reactions, anaphylactic reactions, autoimmune diseases.
pathogenesis of cell injury both of reversible and irreversible cell injury should be mentioned.
2 DIFFERENCES BETWEEN REVERSIBLE AND IRREVERSIBLE CELL INJURY 1. inability of cell to reverse mitochondrial dysfunction on reperfusion or reoxygenation. 2. disturbance in cell membrane function and also in plasma membrane.
morphology of reversible cell injury 1. hydropic change 2. fatty change 3. hyaline change 4. mucoid change.
synonyms of hydropic change cloudy swelling or vacuolar defgenration
etiology of hydropic changes bacterial toxins, burns, high fever, chemicals, poisons, IV administration of hypertonic glucose.
pathogenesis of hydropic change cloudy swelling --- impaired regulation of Na+ and K+--- intracellular accumulation of Na+ and escape of K+--- rapid flow of water into cell --- cellular swelling.
microscopic changes : cells swollen and microvasculature compressed small clear vacuoles seen small cytoplasmic blebs nucleus appear pale.
2 types of hyaline change intracellular extracellular
examples of intracellular hyaline change 1. hyaline droplets 2. hyaline degeneration or zenker's degeneration 3. mallory's hyaline 4. cytoplasmic hyaline inclusions 5. russell's bodies
examples of extracellular hyaline change 1. hyaline degeneration in leiomyomas 2. hyalinised old scar 3. hyaline arteriosclerosis 4. hyalinised glomeruli corpora amylacea
mucoid change : chief constituent is? mucin
morphology of irreversible cell injury includes: 1. autolysis 2. ncerosis 3. apoptosis 4. gangrene 5. pathologic calcification
autolysis? self digestion 3 types: rapid--- pancreas intermediate--- heart, liver and kidney slow--- fibrous tissue
necrosis? etiology? defined as localised area of death of tissues followed by degradation of tissues by hydrolytic enzymes liberated from dead cells. physical and microbial agents,immunological injury.
pathogenesis of necrosis 1.cell digestion by lytic enzymes 2. denaturation of proteins
types of necrosis coagulative liquefactive caseous fat fibrinoid
coagulative : caused by? commonly affected organs? gross and microscopic features? - irreversible focal injury - heart , kidney, spleen - gross: pale , firm, slightly swollen in early stage ; yellowish, softer, shrunken with progression. microscopic: tombstone appearance
liquefaction necrosis: othername ? caused due to ? examples? gross and microscopic features? - colliquative - ischaemic injury and bacterial and fungal infections - infarct brain , abscess cavity - gross: soft with liquefied centre with necrotic debris , cyst wall microscopic: gliosis in brain and proliferating fibroblasts in abscess cavity
caseous nacrosis: caused by? found in? gross and microscopic features ? - TB infection - centre of foci in TB infections - gross: dry cheese , soft, granular and yellowish microscopically : structureless, eosinophillic, granular debris
fat necrosis: caused by? examples? gross and microscopic feature? - blunt trauma, radiation and surgeries - pancreas, breasts etc. - gross : chalky white appearance in calcium soap, yellowish white appearance. microscopic: cloudy appearance
saponification? - seen in fat necrosis - leaked out free fatty acids along with calcium form calcium soap called saponification.
fibrinoid necrosis: caused by ? examples? microscopic feature? - antigen-antibody complexes deposited in walls of blood vessels along with fibrin. - autoimmune diseases, arthus reaction , peptic ulcer etc. - brightly eosinophillic, hyaline - like deposition
Created by: Dt. Anjali
Popular Standardized Tests sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards